Protein Alignment Antp and Hoxc11

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001020013.1
• Gene: Hoxc11 / 109663
• MGIID: 96193
• Length: 304
• Species: Mus musculus
• Alignment Length: 279
• Identity: 70/279 - (25%)
• Similarity: 111/279 - (39%)
• Gaps: 81/279 - (29%)

  Fly   139 LPQV-TQQVTHPQQQQQQPVVYASCKLQAAVGGLGMVPEGGSPPLVDQMSGHHMNAQMT------ 196
            |||. ::|:::|...|..||...|         .|:.|.|         ..||.|:..:
Mouse    51 LPQAPSRQISYPYSAQVPPVREVS---------YGLEPSG---------KWHHRNSYSSCYAAAD 97

  Fly   197 -LPHHMGHPQAQLGYTDVGVPDVTEV-------HQNHHN--------MGMY---QQQSGVPPV-- 240
             |.|....|.:          .|||:       :..||:        .|.|   .:.|.:|..
Mouse    98 ELMHRECLPPS----------TVTEILMKNEGSYGGHHHPSAPHAAPAGFYSSVNKNSVLPQAFD 152

  Fly   241 --------------GAPPQGMMHQGQGPPQ----------MHQGHPGQHTPPSQNPNSQSSGMPS 281
                          ..||.....:.:|.|:          ...|...:....:.||:|..|...:
Mouse   153 RFFDNAYCGGGDAPAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEAEAEEENTNPSSSGSSHSA 217

  Fly   282 PLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQ 346
            ...|...:.....:.||: |..|:::|..|||:||.||.|:.:.:|::::..|.||:||:|||||
Mouse   218 TKEPAKGAAPNAPRTRKK-RCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQ 281

  Fly   347 NRRMKWKKENKTKGEPGSG 365
            |||||.||.::.:.:..||
Mouse   282 NRRMKEKKLSRDRLQYFSG 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	33/195 (17%)
		Homeodomain	298..354	CDD:459649	28/55 (51%)
Hoxc11	NP_001020013.1	DUF3528	42..161	CDD:432284	27/137 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	167..237		12/70 (17%)
		Homeodomain	233..289	CDD:459649	29/56 (52%)