DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Antp and Hoxa2

DIOPT Version :9

Sequence 1:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_036713.2	Gene:	Hoxa2 / 103690123	RGDID:	2813	Length:	372	Species:	Rattus norvegicus

Alignment Length:	186	Identity:	64/186 - (34%)
Similarity:	82/186 - (44%)	Gaps:	58/186 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 PPVGAPPQG-------MMHQGQGPPQMHQG----HPGQH---------TPPSQNPNSQSSGMPS- 281
            |||....|.       :.|....||...|.    :||.|         .|.|....|:.|.:|:
  Rat    26 PPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRQSAGAGGRPKSSPAGSRGSPVPAR 90

  Fly   282 ----PLYPWMRSQFGKCQER-------------------------------KRGRQTYTRYQTLE 311
                |.||||:.:  |..::                               :|.|..||..|.||
  Rat    91 ALQPPEYPWMKEK--KAAKKTALPPAAASTGPACLGHKESLEIADGSGGGSRRLRTAYTNTQLLE 153

  Fly   312 LEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTKGEPGSGGE 367
            ||||||||:||.|.||:|||..|.|||||:|:||||||||.|::.:.|....|.|:
  Rat   154 LEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGK 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	25/123 (20%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	37/52 (71%)
Hoxa2	NP_036713.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	42..96		12/53 (23%)
		Antp-type hexapeptide	96..101		3/4 (75%)
		Homeobox	143..196	CDD:395001	37/52 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..225		4/16 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910