DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Antp and hoxb1

DIOPT Version :9

Sequence 1:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	XP_004918719.1	Gene:	hoxb1 / 100493290	XenbaseID:	XB-GENE-485772	Length:	304	Species:	Xenopus tropicalis

Alignment Length:	374	Identity:	98/374 - (26%)
Similarity:	132/374 - (35%)	Gaps:	123/374 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 GVTDLDAQQMHHYSQNANHQGNMPYPRFPPYDRMPYYNGQGMDQQQQHQVYSRPDSPSSQVGGVM 97
            |.:....:..||:     .||..|:|..|..:.:  |||.|
Frog    18 GTSAYSPRGYHHF-----EQGTPPFPACPGTNDI--YNGDG------------------------ 51

  Fly    98 PQAQTNGQLGVPQQQQQQQQQPSQNQQQQQAQQAPQQLQQQLPQVTQQVTHPQQQQQQPVVYASC 162
             :....|..|||  ....||.||...|..........|....||...|....|       .|||
Frog    52 -RFVVGGGNGVP--SHLHQQNPSYPPQPSAGVPYTNSLTSYTPQTCNQAYGHQ-------AYAS- 105

  Fly   163 KLQAAVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHN 227
                        |:...  :..|.:.:..|                          |..:.|.::
Frog   106 ------------PDADG--IYFQQTAYCSN--------------------------TGANSNSYS 130

  Fly   228 MG---------MYQQQSGVPPVGAPPQGMMHQGQGPPQM-HQGHPGQHTPPSQNPNSQSSGMPSP 282
            .|         .|||.    |.|...||::.....||.| |     :...|| .|:.|:  :|:.
Frog   131 DGYCGAVPGPAQYQQH----PYGQEHQGLLQAYHNPPSMLH-----EEKEPS-CPSEQA--LPNH 183

  Fly   283 LYPWMRSQ------------FGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC 335
            .:.||:.:            ||...::...|..:|..|..|||||||||:||||.||:|||..|.
Frog   184 TFDWMKVKRNPPKTTAKPVDFGLSTQQNTIRTNFTTKQLTELEKEFHFNKYLTRARRVEIAATLE 248

  Fly   336 LTERQIKIWFQNRRMKWKKENK-------TKGEPGSGGEGDEITPPNSP 377
            |.|.|:||||||||||.||..:       .||.....||..:::...||
Frog   249 LNETQVKIWFQNRRMKQKKREREGLAPSAIKGSMKENGEMSDLSSSTSP 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	28/166 (17%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	35/52 (67%)
hoxb1	XP_004918719.1	PTZ00395	<12..>147	CDD:185594	38/214 (18%)
hoxb1	XP_004918719.1	Homeobox	214..267	CDD:365835	35/52 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000