DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Antp and hoxc5

DIOPT Version :9

Sequence 1:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	XP_002936695.2	Gene:	hoxc5 / 100487879	XenbaseID:	XB-GENE-485672	Length:	225	Species:	Xenopus tropicalis

Alignment Length:	240	Identity:	89/240 - (37%)
Similarity:	116/240 - (48%)	Gaps:	38/240 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 VTQQVTHPQQQQQQPVVYASCKLQAAVGGLGMVPE-----------------GGSPPL--VDQMS 187
            ::..|.:...:|.|.|...|.:.....|.:..||.                 |.|..|  :|..|
Frog     1 MSSYVANSFYKQSQNVPAYSMQSYGNYGSVSEVPSSRYCYSGLDLSITFPSPGSSNSLSALDMPS 65

  Fly   188 GHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVPPVGAPPQGMMHQGQ 252
            ..:.|::......||    ..|:|      |....|:..|.|:|.|::....:....:|:
Frog    66 NPNANSERPSCTVMG----SSGHT------VGRGEQSALNSGIYNQKAATTSLEERSKGI----- 115

  Fly   253 GPPQMHQGHPGQHTPPSQNPNSQSSGMPSPLYPWM-RSQFGKCQERKRGRQTYTRYQTLELEKEF 316
               :..:..|.|.||....|..|....|..:|||| :.......:.||.|.:|||||||||||||
Frog   116 ---ESIKTEPAQSTPQGGQPQQQQQQQPPQIYPWMTKLHMSHETDGKRSRTSYTRYQTLELEKEF 177

  Fly   317 HFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTKGE 361
            |||||||||||||||:.|||.|||||||||||||||||:.|.|.:
Frog   178 HFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDTKVKSK 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	36/164 (22%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	47/52 (90%)
hoxc5	XP_002936695.2	Homeobox	161..215	CDD:395001	47/53 (89%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45659
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010