Protein Alignment Antp and nkx2-1

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: XP_002935383.1
• Gene: nkx2-1 / 100135015
• XenbaseID: XB-GENE-485985
• Length: 346
• Species: Xenopus tropicalis
• Alignment Length: 244
• Identity: 58/244 - (23%)
• Similarity: 91/244 - (37%)
• Gaps: 53/244 - (21%)

  Fly   140 PQVTQQVTHPQQQQQQPVVYASCKLQAAVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHP 204
            |.....:..|.::..:.|...|..|.|.:.......:.....:.....||  |..::..:||
 Frog    10 PFSVSDILSPLEESYKKVAMESAGLGAPLSAAYRQSQVSQASMQQHGMGH--NGPVSAAYHM--- 69

  Fly   205 QAQLGYTDVGVPDVTEVHQNHH---NMGMYQQQSGVPP-------------VGAPPQ---GMMHQ 250
                  |..|||.::......:   |:|.....|.:||             .||.|.   ..:.:
 Frog    70 ------TAAGVPQLSHTTMGGYCNGNLGNLGNMSELPPYQDTMRNSSATGWYGANPDPRFSTISR 128

  Fly   251 GQGPPQ-MHQGHPGQHTPPSQNPNSQSSG----MPSPLYPWMRSQFGKCQERKRGRQTYTRYQTL 310
            ..||.. |:.|..|         |..|.|    ..:||         :...|::.|..:::.|..
 Frog   129 FMGPSSGMNMGGLG---------NMGSLGDVGKSMTPL---------QATPRRKRRVLFSQAQVY 175

  Fly   311 ELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTK 359
            |||:.|...:||:...|..:|..:.||..|:||||||.|.|.|::.|.|
 Frog   176 ELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDK 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	32/168 (19%)
		Homeodomain	298..354	CDD:459649	21/55 (38%)
nkx2-1	XP_002935383.1	Homeodomain	163..219	CDD:459649	21/55 (38%)