Protein Alignment ftz and LBX2

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001269359.1
• Gene: LBX2 / 85474
• HGNCID: 15525
• Length: 198
• Species: Homo sapiens
• Alignment Length: 190
• Identity: 49/190 - (25%)
• Similarity: 70/190 - (36%)
• Gaps: 45/190 - (23%)

  Fly   176 PQSQTQKLKNGDFATP--PPTTPTSLPPLEGISTPPQSPGEKSSSAVSQEINHRIV--------- 229
            |::....|...|...|  .|..| |.|.|     |...||..|.....:|:..:..
Human     7 PRTPRTLLSIADILAPRMVPRAP-SAPQL-----PESGPGPTSPLCALEELTSKTFRGLDARALQ 65

  Fly   230 -----TAPN--GAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDI 287
                 ..|:  |.|.|.            :..:::|..:|..|.||||:.|.|.:|:....|..:
Human    66 PSEGRAGPDALGPGPFG------------RKRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGL 118

  Fly   288 ANALSLSERQIKIWFQNRRMKSKKD---RTLDSSPEHCGAGYTAMLPPLEATSTATTGAP 344
            |..|.|:..|:..||||||.|.|:|   ...|.      |...|:.|.:..:.....|||
Human   119 ATRLGLANAQVVTWFQNRRAKLKRDVEEMRADV------ASLRALSPEVLCSLALPEGAP 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	18/89 (20%)
		Homeodomain	255..311	CDD:459649	22/55 (40%)
		KLF1_2_4_N	<321..404	CDD:425360	6/24 (25%)
LBX2	NP_001269359.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46		9/27 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..89		4/37 (11%)
		Homeodomain	86..142	CDD:459649	22/55 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..198		49/190 (26%)