Protein Alignment ftz and BARX2

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_003649.2
• Gene: BARX2 / 8538
• HGNCID: 956
• Length: 279
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 71/276 - (25%)
• Similarity: 100/276 - (36%)
• Gaps: 92/276 - (33%)

  Fly   164 ASEDVDYLDVYSPQSQTQKLKNGDFATPPP----TTPTSLP--PLEGIST---------PPQSPG 213
            :.|..||.:..|..|....|    ...|.|    |...||.  ||..:.|         .|.:||
Human    32 SKETCDYFEKLSLYSVCPSL----VVRPKPLHSCTGSPSLRAYPLLSVITRQPTVISHLVPATPG 92

  Fly   214 -------EKSSSAVSQEINHRIVTAPNGAGDFNWSHIEETLASD----------CKDSKRTRQTY 261
                   .:.:.|||.|       ||.|          |.|||.          .|..:|:|..:
Human    93 IAQALSCHQVTEAVSAE-------APGG----------EALASSESETEQPTPRQKKPRRSRTIF 140

  Fly   262 TRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGY 326
            |..|.:.|||:|...:|::...|:|:|.:|.|::.|:|.|:||||||.||
Human   141 TELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKK--------------- 190

  Fly   327 TAMLPPLEATSTATTGAP---SVPVPMYHHHQTTAAYPAYSHSHSHGYGLLNDYPQQQTHQQYDA 388
             .:|...:...|...|.|   |:|        |:....|....:|...|      |:|..
Human   191 -MVLKGGQEAPTKPKGRPKKNSIP--------TSEEIEAEEKMNSQAQG------QEQLE----- 235

  Fly   389 YPQQYQHQCSYQQHPQ 404
             |.|.|.:....|.|:
Human   236 -PSQGQEELCEAQEPK 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	25/105 (24%)
		Homeodomain	255..311	CDD:459649	23/55 (42%)
		KLF1_2_4_N	<321..404	CDD:425360	16/85 (19%)
BARX2	NP_003649.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..137		9/36 (25%)
		Homeodomain	134..190	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..279		16/77 (21%)