Protein Alignment ftz and nkx3.3

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001013342.2
• Gene: nkx3.3 / 503746
• ZFINID: ZDB-GENE-050306-27
• Length: 240
• Species: Danio rerio
• Alignment Length: 250
• Identity: 59/250 - (23%)
• Similarity: 99/250 - (39%)
• Gaps: 87/250 - (34%)

  Fly   151 SYDQEY----------VTVPTPSASEDVDYLDVYSPQSQTQKLKNGDFATPPPTTPTSLPPLEGI 205
            |:|:||          .:||....:|          .:||:             ..:.:..||.:
Zfish    25 SFDEEYEGEKRTQDSGSSVPVNRGAE----------SAQTR-------------ISSCVLVLESL 66

  Fly   206 STPPQSPGEKSS---SAVSQEINHRIVTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTL 267
            |:...|..|:|:   :::.:..:|.:......:..|..|:.:.:       .||:|..::..|..
Zfish    67 SSDQHSCEEESTGEDNSLERRHDHEMDQQKPQSCSFEDSNPKSS-------KKRSRAAFSHAQVY 124

  Fly   268 ELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPP 332
            |||:.|:..||::...|.|:|.||.|:|.|:||||||||.|:|:.:               |...
Zfish   125 ELERRFNLQRYLSGPERADLAGALKLTETQVKIWFQNRRYKTKRRQ---------------MAAE 174

  Fly   333 LEATSTATTG----------------------APSVPVPMYHHHQTTAAYPAYSH 365
            |..|.|.|..                      :|||| |:|.      ::|.|.:
Zfish   175 LATTPTTTLAKRVAVKVLVRNDQRQYNTEDLPSPSVP-PLYQ------SFPYYPY 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	18/109 (17%)
		Homeodomain	255..311	CDD:459649	27/55 (49%)
		KLF1_2_4_N	<321..404	CDD:425360	13/66 (20%)
nkx3.3	NP_001013342.2	Homeodomain	112..168	CDD:459649	27/55 (49%)