Protein Alignment ftz and MSX1

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_002439.2
• Gene: MSX1 / 4487
• HGNCID: 7391
• Length: 303
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 58/238 - (24%)
• Similarity: 86/238 - (36%)
• Gaps: 71/238 - (29%)

  Fly   192 PPTTPTSLPPLEGI----------STPPQSPGEKSSSAVSQEINHRIV--------------TAP 232
            |....::|.|.||:          ..||.|.|...:.:..:.:.|..|              .:|
Human    73 PGAKESALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESP 137

  Fly   233 NGAGDFNWSHIEE--------------TLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRR 283
            .......|.....              ||... |.:::.|..:|..|.|.||::|...:|::...
Human   138 EKPERTPWMQSPRFSPPPARRLSPPACTLRKH-KTNRKPRTPFTTAQLLALERKFRQKQYLSIAE 201

  Fly   284 RIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPL----------EATST 338
            |.:.:::|||:|.|:||||||||.|:|  |..::..|........||||.          .|...
Human   202 RAEFSSSLSLTETQVKIWFQNRRAKAK--RLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVA 264

  Fly   339 ATTGA--------------PSVPVPMYHHHQTTAAYPAYSHSH 367
            |..||              |..||.:|      .|:..||..|
Human   265 AAAGASLYGASGPFQRAALPVAPVGLY------TAHVGYSMYH 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	14/93 (15%)
		Homeodomain	255..311	CDD:459649	23/55 (42%)
		KLF1_2_4_N	<321..404	CDD:425360	16/71 (23%)
MSX1	NP_002439.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	69..117		9/43 (21%)
		PTZ00449	<105..>248	CDD:185628	35/145 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..174		5/41 (12%)
		Homeodomain	173..229	CDD:459649	24/57 (42%)