Protein Alignment ftz and MEOX1

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_004518.1
• Gene: MEOX1 / 4222
• HGNCID: 7013
• Length: 254
• Species: Homo sapiens
• Alignment Length: 211
• Identity: 67/211 - (31%)
• Similarity: 86/211 - (40%)
• Gaps: 59/211 - (27%)

  Fly   146 ASPAPSYDQEYVTVPTP-SASEDVDYLDVYSPQSQTQKLKNGDF-ATPPPTTPTSLPPLEGISTP 208
            ||..|.|.      ||| |..:..|:|       .|......|| |:....||.|||..|.|.|.
Human    32 ASGLPHYP------PTPFSFHQKPDFL-------ATATAAYPDFSASCLAATPHSLPQEEHIFTE 83

  Fly   209 -----PQSPG------------EKSSSAVSQEINHR---IVTAPNGAGDFNWSHIEETLASDCKD 253
                 ||||.            ....:..|:|:...   :|....|.|| ::..:..|.....|.
Human    84 QHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSSLGLVDTTGGPGD-DYGVLGSTANETEKK 147

  Fly   254 SKRTRQ-----------------------TYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSE 295
            |.|.|:                       .:|:.|..|||.||..:.|:||.||.:||..|.|||
Human   148 SSRRRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSE 212

  Fly   296 RQIKIWFQNRRMKSKK 311
            ||:|:||||||||.|:
Human   213 RQVKVWFQNRRMKWKR 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	33/123 (27%)
		Homeodomain	255..311	CDD:459649	31/78 (40%)
		KLF1_2_4_N	<321..404	CDD:425360
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..178		15/92 (16%)
		Homeodomain	172..228	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..254		1/2 (50%)