Protein Alignment ftz and cdx1

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_989416.1
• Gene: cdx1 / 395055
• XenbaseID: XB-GENE-485396
• Length: 262
• Species: Xenopus tropicalis
• Alignment Length: 244
• Identity: 71/244 - (29%)
• Similarity: 101/244 - (41%)
• Gaps: 38/244 - (15%)

  Fly   115 NPVKK--LKYTPDYF------YTTVEQVKKAPAVSTK--------VTASPAPSYDQEYVTVPTPS 163
            |||:.  |...|..:      |:........|.:::.        ..:|..||.:..:...|.|.
 Frog    16 NPVRHPGLNLNPQNYVPAPPQYSDFPSYHHVPGINSDPHHGQPGGTWSSYTPSREDWHPYGPGPG 80

  Fly   164 ASEDVDYLDVYSPQSQTQKLKNGDFATPPPTTPTSLPPLEGISTPPQSPGEKSSSAVSQEINHRI 228
            ||........:||         .|:....|..|..|||....|..|.||..:..:.........:
 Frog    81 ASSANPAQISFSP---------SDYNPVQPPGPGLLPPSLNSSVSPLSPSAQRRNLYEWMRRTGV 136

  Fly   229 VTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSL 293
            .|:.|..|        :|...|     :.|..||.:|.||||||||::||||.||:.::|.:|:|
 Frog   137 PTSTNSNG--------KTRTKD-----KYRVVYTDHQRLELEKEFHYSRYITIRRKAELAASLAL 188

  Fly   294 SERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPLEATSTATTG 342
            :|||:||||||||.|.:|........:...|..|...||...|:....|
 Frog   189 TERQVKIWFQNRRAKERKVNKKKMQQQSQQASTTTPTPPSVGTTAGMGG 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	30/148 (20%)
		Homeodomain	255..311	CDD:459649	33/55 (60%)
		KLF1_2_4_N	<321..404	CDD:425360	6/22 (27%)
cdx1	NP_989416.1	Caudal_act	13..141	CDD:461413	27/133 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..120		18/86 (21%)
		Homeodomain	151..206	CDD:459649	33/54 (61%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	152..173		12/20 (60%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	191..202		9/10 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..262		8/35 (23%)