Protein Alignment ftz and Nkx2-4

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: XP_038962557.1
• Gene: Nkx2-4 / 366213
• RGDID: 1304985
• Length: 353
• Species: Rattus norvegicus
• Alignment Length: 328
• Identity: 66/328 - (20%)
• Similarity: 99/328 - (30%)
• Gaps: 118/328 - (35%)

  Fly   161 TPSASEDVDYLDVYSPQSQTQKLKNG--DFATP-------------PPTTPTS-LPPLEGISTPP 209
            :|..:......|:.||..:|.|...|  |.|.|             |||.|:| ...:.|:..|.
  Rat     4 SPKHTTPFSVSDILSPIEETYKKFGGVMDGAPPGLGAPLGAAAYRAPPTGPSSQAAAVAGMQPPH 68

  Fly   210 QSPGEKSSSAVSQEINHRIVTA----PNGAGDF-------------------------------- 238
            ...|..:::|.:.........|    |.|...|
  Rat    69 AMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQFPHSAMGSYCNGGLGNMGELPAYTDGMRGGAAA 133

  Fly   239 ------------NWSHIEE----------------TLASDCKDS----------KRTRQTYTRYQ 265
                        .:|.|..                |..:|...|          ::.|..:::.|
  Rat   134 AATGWYGANTDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLAPLHAAAPRRKRRVLFSQAQ 198

  Fly   266 TLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSK---KDRTLDSSPEHCGAGYT 327
            ..|||:.|...:|::...|..:|:.:.|:..|:||||||.|.|.|   ||:......:..|.|..
  Rat   199 VYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGLGPP 263

  Fly   328 AMLPP------------------LEATSTATTG----APSVPVPMYHHHQTTAAYPAYSHSHSHG 370
            ...||                  .....|.|.|    .|..|.|.....:.:::.||.   |..|
  Rat   264 PPPPPPSPRRVAVPVLVKDGKPCQNGAGTPTPGQGGQQPQAPTPASELEELSSSPPAL---HGPG 325

  Fly   371 YGL 373
            .||
  Rat   326 GGL 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	26/166 (16%)
		Homeodomain	255..311	CDD:459649	20/58 (34%)
		KLF1_2_4_N	<321..404	CDD:425360	16/75 (21%)
Nkx2-4	XP_038962557.1	Homeodomain	188..244	CDD:459649	19/55 (35%)