Protein Alignment ftz and pnx

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_840087.1
• Gene: pnx / 352939
• ZFINID: ZDB-GENE-030328-42
• Length: 182
• Species: Danio rerio
• Alignment Length: 241
• Identity: 71/241 - (29%)
• Similarity: 94/241 - (39%)
• Gaps: 84/241 - (34%)

  Fly   169 DYLD--VYSPQSQTQKLKNGDFATPPPTTPTSLPPLEGISTPPQSPGEKSSSAVSQEINHRIVTA 231
            |.||  .::...:|:::.| :..:|..|:||..|                             :|
Zfish    20 DILDPAKFNGTRETREISN-NRESPKTTSPTQEP-----------------------------SA 54

  Fly   232 PNGAGDFNWSHIEETLASDCK-DSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSE 295
            ||.|.           ||..| .|||.|..:|..|...||:.|..:.|::...|..||:||.|||
Zfish    55 PNIAN-----------ASAAKVKSKRIRTAFTLDQLRILERSFQSSHYLSVFERHCIASALGLSE 108

  Fly   296 RQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPLEATSTATTGAPSVPVPMYHHHQTTAAY 360
            .|:||||||||.|.||:  ||.   |.|.         |.:..|.|.....|: ||       |.
Zfish   109 TQVKIWFQNRRTKWKKE--LDG---HGGE---------EQSHCAPTALTQNPI-MY-------AL 151

  Fly   361 PAYSHSHSHGYGLLNDYPQQQTHQQYDAYPQQYQHQCSYQQHPQDL 406
            |.:..:|               |..|  |||| .|..:...|||.|
Zfish   152 PGHHANH---------------HVHY--YPQQ-THYLNTSFHPQML 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	14/80 (18%)
		Homeodomain	255..311	CDD:459649	27/55 (49%)
		KLF1_2_4_N	<321..404	CDD:425360	19/82 (23%)
pnx	NP_840087.1	Important for interaction with tle3a. /evidence=ECO:0000269|PubMed:12642490	1..34		3/13 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..63		13/79 (16%)
		Homeodomain	68..124	CDD:459649	27/55 (49%)