DRSC/TRiP Functional Genomics Resources

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Protein Alignment ftz and BARHL2

DIOPT Version :10

Sequence 1:NP_477498.1 Gene:ftz / 40834 FlyBaseID:FBgn0001077 Length:410 Species:Drosophila melanogaster
Sequence 2:NP_064447.1 Gene:BARHL2 / 343472 HGNCID:954 Length:387 Species:Homo sapiens


Alignment Length:364 Identity:70/364 - (19%)
Similarity:118/364 - (32%) Gaps:115/364 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    70 TTQTVP--PVQPTTPPPKATKRKAEDDAASIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTVE 132
            |..|.|  |:..|..||:                              |......|..:.:....
Human    57 TVGTAPSSPISVTMEPPE------------------------------PHLVADATQHHHHLHHS 91

  Fly   133 QVKKAPAVSTKVTASPAPSYDQEYVTVPTPSASEDVDYLDVYSPQSQTQKLKNGDFATPPPTTPT 197
            |....||.:...:..|.|...|     |.|...         .|....|:|  |..|:.|.|:.:
Human    92 QQPPPPAAAPTQSLQPLPQQQQ-----PLPPQQ---------PPPPPPQQL--GSAASAPRTSTS 140

  Fly   198 SL----------------PPLEGISTPPQSPGEKSSSAVSQEINHRIVTAPNGA----------- 235
            |.                |....:|:|..:| ::.|:||.:....::....:..           
Human   141 SFLIKDILGDSKPLAACAPYSTSVSSPHHTP-KQESNAVHESFRPKLEQEDSKTKLDKREDSQSD 204

  Fly   236 ---------GDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANAL 291
                     ||...:...|:.....|..::.|..::.:|..:||:.|...:|::.:.|:|:|.||
Human   205 IKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAAL 269

  Fly   292 SLSERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTA--------------MLPPLEATSTATTG 342
            :|::.|:|.|:||||.|.|:...:..........|:|              :|..:::|:.|...
Human   270 NLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAA 334

  Fly   343 A---------PSVPVPMYHHHQTTAAYPAYSHSHSHGYG 372
            |         |..|.|....       |.......||.|
Human   335 AAMYSSMYRTPPAPHPQLQR-------PLVPRVLIHGLG 366

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ftzNP_477498.1 FTZ 1..248 CDD:397787 35/215 (16%)
Homeodomain 255..311 CDD:459649 20/55 (36%)
KLF1_2_4_N <321..404 CDD:425360 13/75 (17%)
BARHL2NP_064447.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..145 25/133 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 157..240 12/83 (14%)
Homeodomain 233..289 CDD:459649 20/55 (36%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 367..387 70/364 (19%)

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