Protein Alignment ftz and HOXC10

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_059105.2
• Gene: HOXC10 / 3226
• HGNCID: 5122
• Length: 342
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 82/294 - (27%)
• Similarity: 115/294 - (39%)
• Gaps: 85/294 - (28%)

  Fly    84 PKATKRKAEDDAASIIAAVEERPSTLRAL---------------LTNPVKKLKYTPDY------- 126
            |..:||   |:.:|...|:...||.|..|               :..|:....|.|..
Human    51 PSLSKR---DEGSSPSLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCC 112

  Fly   127 FYTTVEQVKKAPAV---STKVTAS-------PAPSYDQEYVTVPTPSASEDVDYL----DVYSPQ 177
            .|:..::.|..|..   |..:..|       |.|||   |...|:.||.:...:.    |..:|.
Human   113 MYSAEKRAKSGPEAALYSHPLPESCLGEHEVPVPSY---YRASPSYSALDKTPHCSGANDFEAPF 174

  Fly   178 SQTQKLK---------------------NGDFATPPPTTPTSLPPLEGISTPPQSPGEK------ 215
            .|...|.                     ..|..||   :|..:...:.::.|..||.|.
Human   175 EQRASLNPRAEHLESPQLGGKVSFPETPKSDSQTP---SPNEIKTEQSLAGPKGSPSESEKERAK 236

  Fly   216 ---SSSAVSQEINHRIVTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNR 277
               ||...|.......:.|.|..|  ||        ...|..::.|..||::|||||||||.||.
Human   237 AADSSPDTSDNEAKEEIKAENTTG--NW--------LTAKSGRKKRCPYTKHQTLELEKEFLFNM 291

  Fly   278 YITRRRRIDIANALSLSERQIKIWFQNRRMKSKK 311
            |:||.||::|:..::|::||:||||||||||.||
Human   292 YLTRERRLEISKTINLTDRQVKIWFQNRRMKLKK 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	46/229 (20%)
		Homeodomain	255..311	CDD:459649	33/55 (60%)
		KLF1_2_4_N	<321..404	CDD:425360
HOXC10	NP_059105.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..271		17/96 (18%)
		Homeodomain	269..325	CDD:459649	33/55 (60%)