Protein Alignment ftz and HOXB7

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_004493.3
• Gene: HOXB7 / 3217
• HGNCID: 5118
• Length: 217
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 62/281 - (22%)
• Similarity: 99/281 - (35%)
• Gaps: 88/281 - (31%)

  Fly    87 KKVTSPTKCEVLFEGFGDHSDVLQPPKISNVRVEHGP-------------RDHLTVRSNVH---L 135
            |||.:.::.:||.        :.:|.||.|     ||             ||..|.|.|..   .
Human     6 KKVANSSRSQVLL--------MWKPDKIQN-----GPCNAEKQILTSRLLRDAETCRQNFRNFPY 57

  Fly   136 PCVKLRLVSSQRTPERMIVSNYDVSIVDLRGEVECRMACIANQLYLMGCFSGRPEMDIELRNTDP 200
            |.|        ..|.:.:....::.:..||.||..:.. |...|.|....|..|.   |:| |..
Human    58 PDV--------AGPRKALSQLRELCLKWLRPEVHSKEQ-ILELLVLEQFLSILPG---EVR-TWV 109

  Fly   201 NAQY----QVSIPMVEESIRRCLLSAVTNINLSEEMPEERNTFADTFSRTIYNPPTHS-PSGTMR 260
            |:||    :..:.:||:..:.....|..|..|.:|:|||              .|.|: .:|.:.
Human   110 NSQYPENSEEVVALVEDLAQILEEEAPQNSALPQEIPEE--------------DPKHALETGWLN 160

  Fly   261 NSYNNYDTNLHVDAYGTQSSHRSNSPSGDVPEMFKKLNESHLISP----SYNTNSIPNKMRIKVI 321
            :..             |:.|...|..:.|:.:     .:..|:.|    .|.|.::.|...:
Human   161 DLV-------------TKESVTFNDVAVDITQ-----EDWELMRPVEKELYKTVTLQNYWNM--- 204

  Fly   322 KASRLGREVSQPFVNVEMDEP 342
              ..||..|.:|.|...::||
Human   205 --VSLGLTVYRPTVIPILEEP 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	43/180 (24%)
		Homeodomain	255..311	CDD:459649	9/59 (15%)
		KLF1_2_4_N	<321..404	CDD:425360	7/22 (32%)
HOXB7	NP_004493.3	Antp-type hexapeptide	126..131		0/4 (0%)
		Homeodomain	138..194	CDD:459649	15/87 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..217		6/27 (22%)