Protein Alignment ftz and TLX1

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: XP_011538046.1
• Gene: TLX1 / 3195
• HGNCID: 5056
• Length: 342
• Species: Homo sapiens
• Alignment Length: 190
• Identity: 50/190 - (26%)
• Similarity: 79/190 - (41%)
• Gaps: 42/190 - (22%)

  Fly   189 ATPPPTTPTSLPPLEGIS-----TPPQSPGEK-----------SSSAVSQEINH--RIVTAPNGA 235
            ||..||.| |:|.:.|::     |.|.....:           |...|::.|.|  :..|.|.
Human   151 ATGLPTVP-SVPAMPGVNNLTGLTFPWMESNRRYTKDRFTVALSPFTVTRRIGHPYQNRTPPK-- 212

  Fly   236 GDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKI 300
                              .|:.|.::||.|..||||.||..:|:....|..:|.||.:::.|:|.
Human   213 ------------------KKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKT 259

  Fly   301 WFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPLEATSTATTGAPSVPV-PMYHHHQTTAA 359
            ||||||.|.::....:...|...|  ..:|..|:..:...:.|..:|. |:..|:.:..|
Human   260 WFQNRRTKWRRQTAEEREAERQQA--NRILLQLQQEAFQKSLAQPLPADPLCVHNSSLFA 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	16/76 (21%)
		Homeodomain	255..311	CDD:459649	25/55 (45%)
		KLF1_2_4_N	<321..404	CDD:425360	8/40 (20%)
TLX1	XP_011538046.1	Homeodomain	214..270	CDD:459649	25/55 (45%)