Protein Alignment ftz and Hoxc10

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001295565.1
• Gene: Hoxc10 / 315338
• RGDID: 1307250
• Length: 342
• Species: Rattus norvegicus
• Alignment Length: 296
• Identity: 83/296 - (28%)
• Similarity: 114/296 - (38%)
• Gaps: 89/296 - (30%)

  Fly    84 PKATKRKAEDDAASIIAAVEERPSTLRAL---------------LTNPVKKLKYTPDY------- 126
            |..:||   |:..|...|:...||.|..|               :..|:....|.|..
  Rat    51 PSLSKR---DEGGSPNLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCC 112

  Fly   127 FYTTVEQVKKAPAVSTKVTASPAPSYDQEYVTVPTPS---ASEDVDYLD---------------- 172
            .|:..::.|..|..:  :.:.|.|........||.||   ||.....||
  Rat   113 MYSAEKRAKSGPEAA--LYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCAGANEFEAPFE 175

  Fly   173 -----------VYSPQ-------SQTQKLKNGDFATPPPTTPTSLPPLEGISTPPQSPGEK---- 215
                       :.|||       .:|.|   .|..||   :|..:...:.:..|..||.|.
  Rat   176 QRASLNPRTEHLESPQLGGKVSFPETPK---SDSQTP---SPNEIKTEQSLVGPKASPSESEKER 234

  Fly   216 -----SSSAVSQEINHRIVTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHF 275
                 ||...|.......:.|.|..|  ||        ...|..::.|..||::|||||||||.|
  Rat   235 AKTADSSPDTSDNEAKEEIKAENTTG--NW--------LTAKSGRKKRCPYTKHQTLELEKEFLF 289

  Fly   276 NRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKK 311
            |.|:||.||::|:..::|::||:||||||||||.||
  Rat   290 NMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKK 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	47/231 (20%)
		Homeodomain	255..311	CDD:459649	33/55 (60%)
		KLF1_2_4_N	<321..404	CDD:425360
Hoxc10	NP_001295565.1	Homeodomain	269..325	CDD:459649	33/55 (60%)