DRSC/TRiP Functional Genomics Resources

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Protein Alignment ftz and Nkx6-2

DIOPT Version :10

Sequence 1:NP_477498.1 Gene:ftz / 40834 FlyBaseID:FBgn0001077 Length:410 Species:Drosophila melanogaster
Sequence 2:NP_001101028.1 Gene:Nkx6-2 / 309095 RGDID:1307280 Length:277 Species:Rattus norvegicus


Alignment Length:132 Identity:39/132 - (29%)
Similarity:62/132 - (46%) Gaps:22/132 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   198 SLPPLEGISTPPQSPGE--KSSSAVSQEINHRIVTAPNGAGDFNWSHI-------EETLASDC-- 251
            |||.|.|:::   |.|.  ..::||::.....:...| |.....|..:       :..||...  
  Rat    78 SLPRLNGLAS---SAGVYFGPAAAVARGYPKPLAELP-GRPPIFWPGVVQGSPWRDPRLAGSAQA 138

  Fly   252 -----KDSKR--TRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKS 309
                 ||.|:  :|.|::..|...|||.|...:|:....|..:|.:|.::|.|:|:||||||.|.
  Rat   139 GGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKW 203

  Fly   310 KK 311
            :|
  Rat   204 RK 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ftzNP_477498.1 FTZ 1..248 CDD:397787 12/58 (21%)
Homeodomain 255..311 CDD:459649 22/57 (39%)
KLF1_2_4_N <321..404 CDD:425360
Nkx6-2NP_001101028.1 Homeodomain 147..205 CDD:459649 22/57 (39%)
Blue background indicates that the domain is not in the aligned region.

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