Protein Alignment ftz and nkx2.5

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_571496.2
• Gene: nkx2.5 / 30696
• ZFINID: ZDB-GENE-980526-321
• Length: 314
• Species: Danio rerio
• Alignment Length: 195
• Identity: 55/195 - (28%)
• Similarity: 81/195 - (41%)
• Gaps: 52/195 - (26%)

  Fly   244 EETLASDCK--DSKRTRQ--------TYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQI 298
            :|....|.|  |::|.:|        .:::.|..|||:.|...:|::...|..:||.|.|:..|:
Zfish   121 QEDPGEDLKLDDAERPKQRKRRKPRVLFSQAQVYELERRFKQQKYLSAPERDHLANVLKLTSTQV 185

  Fly   299 KIWFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPP---------------LEATSTATTGAPSVPV 348
            ||||||||.|.|:.|. |.:.|..|     :.||               |..|||..|.
Zfish   186 KIWFQNRRYKCKRQRQ-DQTLEMVG-----IAPPRRISVPVLVRDGKPCLGDTSTYNTS------ 238

  Fly   349 PMYH---HHQTTAAYPAYSHSHSHGYGLLN-DYPQQQTHQQYDAYPQQYQH---------QCSYQ 400
              |:   :|.|...|||:|:..|.|....: :||...:..|.......|.:         |.|:|
Zfish   239 --YNVGINHFTYNTYPAFSNFPSPGNSNYSCNYPSSMSSIQPSQSNSNYMNFGVGDLNNVQASFQ 301

  Fly   401  400
            Zfish   302  301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	1/3 (33%)
		Homeodomain	255..311	CDD:459649	23/63 (37%)
		KLF1_2_4_N	<321..404	CDD:425360	24/108 (22%)
nkx2.5	NP_571496.2	Homeodomain	142..198	CDD:459649	21/55 (38%)