Protein Alignment ftz and Nkx1-1

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: XP_234082.6
• Gene: Nkx1-1 / 298981
• RGDID: 1564874
• Length: 443
• Species: Rattus norvegicus
• Alignment Length: 339
• Identity: 88/339 - (25%)
• Similarity: 126/339 - (37%)
• Gaps: 86/339 - (25%)

  Fly    69 VTTQTVPPVQPT--TPPPKAT--------KRKAEDDAASIIAAVEERPSTLRALLTNPVKKLKYT 123
            |...|..|..|.  .|.|.|:        :|:|...|..:.||....|::              |
  Rat   109 VVPATCAPCAPAACVPVPAASGRSPRAELERRALSAATGVAAATGAEPTS--------------T 159

  Fly   124 PDYFYTTVEQVKKAPAVSTKVTASPAPSYDQEYVTVPTPSASEDVDYLDVYSPQSQTQKLKNGD- 187
            .|.:     :..:|.|......:..:|:.|.|   ...|...||.|..........|::.:.|.
  Rat   160 GDSY-----RADEAEANGYSSGSGRSPTADSE---DEAPEEDEDEDQAPEVQDVQGTEEPRGGSG 216

  Fly   188 -------------FATPPPTTPTSLPPLEGISTPPQSPGEKSSSAVSQEINHRIVTAPNGAGDFN 239
                         .....|....:.|...|.|  |.:||...::|.:....    :.|.||....
  Rat   217 GLGARGSGCSGAAEVEASPVDEAAAPGPRGNS--PGAPGPPVTAAGAGNAG----STPQGAAVAT 275

  Fly   240 WSHIEETLASDCKDSK--RTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWF 302
            ....:.| .||.|..|  |.|..:|..|.:.||.:|...||::...|:::|.:|||:|.|:||||
  Rat   276 KPKRKRT-GSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWF 339

  Fly   303 QNRRMKSKKDRT-LDSS--------------PEHCGAGYTAMLPPLEATSTATTGAPSVPV--PM 350
            ||||.|.||... .|:|              |   |||....|.||         :||.|:  |:
  Rat   340 QNRRTKWKKQNPGADTSAPTGGGGGPGPGAGP---GAGLPGGLSPL---------SPSPPMGAPL 392

  Fly   351 YHHHQTTAAYPAYS 364
            ..|  ..|.|||:|
  Rat   393 ALH--GPAGYPAHS 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	38/202 (19%)
		Homeodomain	255..311	CDD:459649	26/57 (46%)
		KLF1_2_4_N	<321..404	CDD:425360	16/46 (35%)
Nkx1-1	XP_234082.6	Homeodomain	292..348	CDD:459649	25/55 (45%)