Protein Alignment ftz and Pdx1

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_074043.4
• Gene: Pdx1 / 29535
• RGDID: 62387
• Length: 283
• Species: Rattus norvegicus
• Alignment Length: 200
• Identity: 68/200 - (34%)
• Similarity: 93/200 - (46%)
• Gaps: 50/200 - (25%)

  Fly   190 TPPPTTPTSLPPLE----------------GISTPPQSPGEKSSSAVSQEINHRIVTAPNGAGDF 238
            :||..:|..:|||.                |::.||..|....:.....|...| |..|     |
  Rat    61 SPPDISPYEVPPLADDPAGAHLHHHLPAQLGLAHPPPGPFPNGTETGGLEEPSR-VHLP-----F 119

  Fly   239 NW-----SHIEET------LASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALS 292
            .|     :|..::      .|::.:::||||..|||.|.|||||||.||:||:|.||:::|..|:
  Rat   120 PWMKSTKAHAWKSQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLN 184

  Fly   293 LSERQIKIWFQNRRMKSKKDRTLDSS------------PEH-C----GAGYTAMLPPLEATSTAT 340
            |:||.|||||||||||.||:.....|            ||. |    |....|:.||........
  Rat   185 LTERHIKIWFQNRRMKWKKEEDKKRSSGTTSGGGGGEEPEQDCAVTSGEELLALPPPPPPGGAVP 249

  Fly   341 TGAPS 345
            :|.|:
  Rat   250 SGVPA 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	17/84 (20%)
		Homeodomain	255..311	CDD:459649	38/55 (69%)
		KLF1_2_4_N	<321..404	CDD:425360	7/29 (24%)
Pdx1	NP_074043.4	Transactivation domain	13..73		4/11 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..81		6/19 (32%)
		Antp-type hexapeptide	118..123		3/9 (33%)
		Homeodomain	147..203	CDD:459649	38/55 (69%)
		Nuclear localization signal. /evidence=ECO:0000250	197..203		4/5 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..283		12/53 (23%)