Protein Alignment ftz and Hoxd1

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001099354.1
• Gene: Hoxd1 / 288151
• RGDID: 1309179
• Length: 328
• Species: Rattus norvegicus
• Alignment Length: 344
• Identity: 88/344 - (25%)
• Similarity: 120/344 - (34%)
• Gaps: 80/344 - (23%)

  Fly    24 PHSLPPTYYDNSGSNAYYQNTSNYQGYYPQESYSESCYYYNNQEQVTTQTVPPVQPTTPPPKATK 88
            |.:|.|.:...||..|:.                 ||..........:..|.|.||..|.|.|::
  Rat    37 PVALQPAFPLGSGDGAFV-----------------SCLPLAAARPTPSPPVAPAQPPGPQPAASR 84

  Fly    89 RKAEDDAASIIAAVEERPSTLRALLTNPVKKLKY-----TPDYFYTTVEQVKKAPAVSTKVTASP 148
            .     |...:....||.:.       |....:|     .|.:.:         |....:.....
  Rat    85 Y-----APCTLEGAYERGAA-------PASAAEYGFLGSGPAFDF---------PGALGRAADDS 128

  Fly   149 APSYDQEYVTVPTPSA------SEDVDYLDVYSPQSQTQKLKNGDFATPPPTTPTSLPPLEGIST 207
            .|..  .|.|....|:      |..||:.....|......||......|.|....|  |..|...
  Rat   129 GPHV--HYATSAVFSSGGSFLLSGQVDFAAFAEPGPFPACLKEPADGHPGPFQTVS--PAPGACP 189

  Fly   208 PPQSPGEKSSSAVSQEINHRIVTAPNGAGDFNWSHIEETLASDCK--------DSKRTRQTYTRY 264
            .|.||    :|.:           |.....|.|..::.......|        .|...|..::..
  Rat   190 KPASP----TSGL-----------PAAHSTFEWMKVKRNAPKKSKLSEYGATSPSSAIRTNFSTK 239

  Fly   265 QTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTAM 329
            |..|||||||||:|:||.||::|||.|.|::.|:||||||||||.|| |..:.......:..:..
  Rat   240 QLTELEKEFHFNKYLTRARRMEIANCLQLNDTQVKIWFQNRRMKQKK-REREGLLATAASVASLQ 303

  Fly   330 LPPLEAT---STATTGAPS 345
            ||..|.:   |....|:||
  Rat   304 LPGSETSPIKSGRNLGSPS 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	44/234 (19%)
		Homeodomain	255..311	CDD:459649	32/55 (58%)
		KLF1_2_4_N	<321..404	CDD:425360	7/28 (25%)
Hoxd1	NP_001099354.1	COG5576	<208..325	CDD:227863	44/116 (38%)
		Homeodomain	233..286	CDD:459649	32/52 (62%)