Protein Alignment ftz and VAX2

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_036608.1
• Gene: VAX2 / 25806
• HGNCID: 12661
• Length: 290
• Species: Homo sapiens
• Alignment Length: 196
• Identity: 58/196 - (29%)
• Similarity: 77/196 - (39%)
• Gaps: 45/196 - (22%)

  Fly   201 PLEGISTPPQSP-GEKSSSAVSQEINHRIVTAPNGAGDFNWSHIEETLASDCKDS---------- 254
            |.|...|...|| |.:.|.|.|.        ...|.|:.:  |....|..|.|.:
Human    43 PTEVAGTSASSPAGSRESGADSD--------GQPGPGEAD--HCRRILVRDAKGTIREIVLPKGL 97

  Fly   255 -----KRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRT 314
                 ||||.::|..|...||.||...:|:..|.|.::|..|:|||.|:|:||||||.|.|||::
Human    98 DLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQS 162

  Fly   315 LD------SSPEHCGA----------GYTAMLPPLEATSTATTGAPSVPVPMYHHHQTTAAYPAY 363
            .|      ||.....|          |....:|...:....|...|.:|.   .|..|:...|..
Human   163 RDLEKRASSSASEAFATSNILRLLEQGRLLSVPRAPSLLALTPSLPGLPA---SHRGTSLGDPRN 224

  Fly   364 S 364
            |
Human   225 S 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	12/47 (26%)
		Homeodomain	255..311	CDD:459649	27/55 (49%)
		KLF1_2_4_N	<321..404	CDD:425360	10/54 (19%)
VAX2	NP_036608.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..75		11/41 (27%)
		Homeodomain	103..159	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	205..240		6/24 (25%)