Protein Alignment ftz and Nkx2-1

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: XP_006240178.1
• Gene: Nkx2-1 / 25628
• RGDID: 3866
• Length: 423
• Species: Rattus norvegicus
• Alignment Length: 369
• Identity: 74/369 - (20%)
• Similarity: 120/369 - (32%)
• Gaps: 114/369 - (30%)

  Fly   106 PSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAP--------AVSTKVTASPAPSYDQEYVTVPTP 162
            |.|.|...||    .:..|....:.:.:.:..|        |:|.:...|.:|.:       .||
  Rat     8 PKTWRRAKTN----ARQPPSLHSSQLRRTRSTPLRVHPTRSALSRRRIMSMSPKH-------TTP 61

  Fly   163 -SASEDVDYLDVYSPQSQTQK---LKNGDFATP----------PPTTP----------------- 196
             |.|      |:.||..::.|   ::.|....|          ||...
  Rat    62 FSVS------DILSPLEESYKKVGMEGGGLGAPLAAYRQGQAAPPAAAMQQHAVGHHGAVTAAYH 120

  Fly   197 -------------------------TSLPPLE-------------GISTPPQSPGEKSSSAVSQE 223
                                     :.|||.:             |.:..|:.|........:..
  Rat   121 MTAAGVPQLSHSAVGGYCNGNLGNVSELPPYQDTMRNSASGPGWYGANPDPRFPAISRFMGPASG 185

  Fly   224 INHRIVTAPNGAGDFNWSHIEETLASDCKDSKRTRQT-YTRYQTLELEKEFHFNRYITRRRRIDI 287
            :|   ::...|.|..  ..:.:.:|......:|.|:. :::.|..|||:.|...:|::...|..:
  Rat   186 MN---MSGMGGLGSL--GDVSKNMAPLPSAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHL 245

  Fly   288 ANALSLSERQIKIWFQNRRMKSK---KDRTLDSSPEH-----CGAGYTAMLPPLEATSTATTGAP 344
            |:.:.|:..|:||||||.|.|.|   ||:......:.     .|.|..|..|..:.....:....
  Rat   246 ASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQLQQDSGGGGGGGGGAGCPQQQQAQQQSPRRV 310

  Fly   345 SVPVPMYHHHQTTAAYPAYSHSHSHGYGLLNDYPQQQTHQQYDA 388
            :|||.:.......|..||      .|...|..:.|||..||..|
  Rat   311 AVPVLVKDGKPCQAGAPA------PGAASLQGHAQQQAQQQAQA 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	32/218 (15%)
		Homeodomain	255..311	CDD:459649	21/59 (36%)
		KLF1_2_4_N	<321..404	CDD:425360	18/73 (25%)
Nkx2-1	XP_006240178.1	Homeodomain	213..269	CDD:459649	20/55 (36%)