Protein Alignment ftz and Tlx1

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: XP_006526978.1
• Gene: Tlx1 / 21908
• MGIID: 98769
• Length: 345
• Species: Mus musculus
• Alignment Length: 190
• Identity: 50/190 - (26%)
• Similarity: 79/190 - (41%)
• Gaps: 42/190 - (22%)

  Fly   189 ATPPPTTPTSLPPLEGIS-----TPPQSPGEK-----------SSSAVSQEINH--RIVTAPNGA 235
            ||..||.| |:|.:.|::     |.|.....:           |...|::.|.|  :..|.|.
Mouse   154 ATGLPTVP-SVPAVPGVNNLTGLTFPWMESNRRYTKDRFTVALSPFTVTRRIGHPYQNRTPPK-- 215

  Fly   236 GDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKI 300
                              .|:.|.::||.|..||||.||..:|:....|..:|.||.:::.|:|.
Mouse   216 ------------------KKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKT 262

  Fly   301 WFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPLEATSTATTGAPSVPV-PMYHHHQTTAA 359
            ||||||.|.::....:...|...|  ..:|..|:..:...:.|..:|. |:..|:.:..|
Mouse   263 WFQNRRTKWRRQTAEEREAERQQA--NRILLQLQQEAFQKSLAQPLPADPLCVHNSSLFA 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	16/76 (21%)
		Homeodomain	255..311	CDD:459649	25/55 (45%)
		KLF1_2_4_N	<321..404	CDD:425360	8/40 (20%)
Tlx1	XP_006526978.1	Homeodomain	217..273	CDD:459649	25/55 (45%)