Protein Alignment ftz and Pdx1

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_032840.1
• Gene: Pdx1 / 18609
• MGIID: 102851
• Length: 284
• Species: Mus musculus
• Alignment Length: 261
• Identity: 78/261 - (29%)
• Similarity: 110/261 - (42%)
• Gaps: 66/261 - (25%)

  Fly   128 YTTVEQVKKAPAVSTKVTASPAPSYDQE-----YV-TVPTPSASEDVDYLDVYSPQSQTQKLKNG 186
            |....|:.|.|....:   .|.|.:...     |: ..|.|.           .|...|..|.:.
Mouse     7 YYAATQLYKDPCAFQR---GPVPEFSANPPACLYMGRQPPPP-----------PPPQFTSSLGSL 57

  Fly   187 DFATPPPTTPTSLPPLE-----------------GISTPPQSPGEKSSSAVSQEINHRIVTAPNG 234
            :..:||..:|..:|||.                 |::.||..|....:.....|..:| |..|
Mouse    58 EQGSPPDISPYEVPPLASDDPAGAHLHHHLPAQLGLAHPPPGPFPNGTEPGGLEEPNR-VQLP-- 119

  Fly   235 AGDFNWSHIEETLA-------------SDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRID 286
               |.|  ::.|.|             ::.:::||||..|||.|.|||||||.||:||:|.||::
Mouse   120 ---FPW--MKSTKAHAWKGQWAGGAYTAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVE 179

  Fly   287 IANALSLSERQIKIWFQNRRMKSKKD---RTLDSSPEHCGAGYTAMLPPLEATSTATTGAPSVPV 348
            :|..|:|:||.|||||||||||.||:   :....:|...|.|...     |.....|:|...:.|
Mouse   180 LAVMLNLTERHIKIWFQNRRMKWKKEEDKKRSSGTPSGGGGGEEP-----EQDCAVTSGEELLAV 239

  Fly   349 P 349
            |
Mouse   240 P 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	29/142 (20%)
		Homeodomain	255..311	CDD:459649	38/55 (69%)
		KLF1_2_4_N	<321..404	CDD:425360	7/29 (24%)
Pdx1	NP_032840.1	Transactivation domain. /evidence=ECO:0000250	13..73		14/73 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..116		18/97 (19%)
		Antp-type hexapeptide	119..124		3/11 (27%)
		Homeodomain	148..204	CDD:459649	38/55 (69%)
		Nuclear localization signal	198..204		4/5 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	202..284		10/44 (23%)