Protein Alignment ftz and Nkx3-1

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_035051.1
• Gene: Nkx3-1 / 18095
• MGIID: 97352
• Length: 237
• Species: Mus musculus
• Alignment Length: 235
• Identity: 56/235 - (23%)
• Similarity: 93/235 - (39%)
• Gaps: 65/235 - (27%)

  Fly   175 SPQSQTQKL--------------KNGDFATPPPTTPTSLPPLEGISTPPQSPGEKSSSAVSQEIN 225
            :|.:|:::|              ::|..:..|..:|.  |..:....|.::.|...:......|.
Mouse    22 APPTQSKRLTSFLIQDILRDRAERHGGHSGNPQHSPD--PRRDSAPEPDKAGGRGVAPEDPPSIR 84

  Fly   226 H---RIVTAPNGAGDFNWSHIEETLASDCKDS---------------KRTRQTYTRYQTLELEKE 272
            |   ...|.|.....|      ||...||:.:               ||:|..::..|.:|||::
Mouse    85 HSPAETPTEPESDAHF------ETYLLDCEHNPGDLASAPQVTKQPQKRSRAAFSHTQVIELERK 143

  Fly   273 FHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLD-------SSPEHCGAGYTAML 330
            |...:|::...|..:|..|.|:|.|:||||||||.|:|:.:..:       :||        ..|
Mouse   144 FSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSEDLGVLEKNSP--------LSL 200

  Fly   331 PPLEATSTATTGAPSVPVPMYHHHQTTAAYPAYSHSHSHG 370
            |.|:..|..:|...||          ..:||.|.:.:..|
Mouse   201 PALKDDSLPSTSLVSV----------YTSYPYYPYLYCLG 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	16/89 (18%)
		Homeodomain	255..311	CDD:459649	24/55 (44%)
		KLF1_2_4_N	<321..404	CDD:425360	11/50 (22%)
Nkx3-1	NP_035051.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..96		13/75 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	108..130		2/21 (10%)
		Homeodomain	126..182	CDD:459649	24/55 (44%)