Protein Alignment ftz and Msx2

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_038629.2
• Gene: Msx2 / 17702
• MGIID: 97169
• Length: 267
• Species: Mus musculus
• Alignment Length: 275
• Identity: 68/275 - (24%)
• Similarity: 107/275 - (38%)
• Gaps: 69/275 - (25%)

  Fly   146 ASPAP-----SYDQEYVTV-----PTPSASEDVDYLDVYSPQSQTQKLKNGDFAT--------PP 192
            |||..     |.|:|...|     |.|..:|.       |.:.:..|:.:..|:.        ||
Mouse     2 ASPTKGGDLFSSDEEGPAVLAGPGPGPGGAEG-------SAEERRVKVSSLPFSVEALMSDKKPP 59

  Fly   193 PTTPTSLPP----LEGISTPPQSPGE-----KSSSAVSQEINHRIVTAPNGAGDFNW-------- 240
            ..:| ::||    ...:..|...||.     .|...:.:......|.:.|......|
Mouse    60 KESP-AVPPDCASAGAVLRPLLLPGHGVRDAHSPGPLVKPFETASVKSENSEDGAPWIQEPGRYS 123

  Fly   241 ---SHIEETLAS--DCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKI 300
               .|:..|..:  ..|.:::.|..:|..|.|.||::|...:|::...|.:.:::|:|:|.|:||
Mouse   124 PPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKI 188

  Fly   301 WFQNRRMKSKKDRTLDSSPEHCGAGYTAMLP-----------PLEATSTATTGA------PSVPV 348
            ||||||.|:|  |..::..|........|||           ||:|.|  ..||      |.:|:
Mouse   189 WFQNRRAKAK--RLQEAELEKLKMAAKPMLPSGFSLPFPINSPLQAAS--IYGASYPFHRPVLPI 249

  Fly   349 PMYHHHQTTAAYPAY 363
            |....:.|...|..|
Mouse   250 PPVGLYATPVGYGMY 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	27/139 (19%)
		Homeodomain	255..311	CDD:459649	22/55 (40%)
		KLF1_2_4_N	<321..404	CDD:425360	15/60 (25%)
Msx2	NP_038629.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42		11/46 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..132		4/27 (15%)
		Homeodomain	143..199	CDD:459649	23/57 (40%)