DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ftz and nob-1

DIOPT Version :9

Sequence 1:	NP_477498.1	Gene:	ftz / 40834	FlyBaseID:	FBgn0001077	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_001369824.1	Gene:	nob-1 / 176641	WormBaseID:	WBGene00003779	Length:	243	Species:	Caenorhabditis elegans

Alignment Length:	210	Identity:	67/210 - (31%)
Similarity:	94/210 - (44%)	Gaps:	37/210 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 APAVSTKVTASPAPSYDQEYVTVPT--PSASE-----DVDYLDVY-SPQSQTQKLKNGDFATPPP 193
            :|.::...|....|.....|...|:  |:|:|     :..|.|.| :|.:.|     |.::...|
Worm    56 SPQLAPSSTGMVMPGTAGMYGFGPSRMPTANEFGMMMNPVYTDFYQNPLAST-----GWYSYGQP 115

  Fly   194 ---TTPTSLPPLEGISTPPQSPGEKSSSAVSQEINHRIVTAPNGAGDFNW--SHIEETLASDCKD 253
               |...|:|.|:|..:....|....|||         .|.||.|....|  ||          |
Worm   116 YQFTANYSIPSLDGNLSDITIPTTAGSSA---------ATTPNAAMHLPWAISH----------D 161

  Fly   254 SKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSS 318
            .|:.||.|.:.|...||.|:..|:|:|.:||.:::..|.|.|:|:|:||||||||.||.|...|.
Worm   162 GKKKRQPYKKDQISRLEYEYSVNQYLTNKRRSELSAQLMLDEKQVKVWFQNRRMKDKKLRQRHSG 226

  Fly   319 PEHCGAGYTAMLPPL 333
            |...||..|..:..|
Worm   227 PFPHGAPVTPCIERL 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:281812	31/123 (25%)
ftz	NP_477498.1	Homeobox	257..310	CDD:278475	25/52 (48%)
nob-1	NP_001369824.1	Homeobox	165..219	CDD:395001	25/53 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910