Protein Alignment ftz and DLX6

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_005213.3
• Gene: DLX6 / 1750
• HGNCID: 2919
• Length: 293
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 71/306 - (23%)
• Similarity: 104/306 - (33%)
• Gaps: 108/306 - (35%)

  Fly   163 SASEDVDYLDVYSPQSQTQKLKNGDFATPPPTTPTSLPPLEGISTPPQSPGEKSSSAVS------ 221
            |.|..:::......|.|.|:.:......|||..|          .|||...::||.|::
Human    17 SKSAFMEFGQQQQQQQQQQQQQQQQQQQPPPPPP----------PPPQPHSQQSSPAMAGAHYPL 71

  Fly   222 --------------------QEINHRIVTAPNGAGDFN---------WSHIE------------- 244
                                |..:|....|..|...:|         .||.:
Human    72 HCLHSAAAAAAAGSHHHHHHQHHHHGSPYASGGGNSYNHRSLAAYPYMSHSQHSPYLQSYHNSSA 136

  Fly   245 --ETLASDCKDSKRT----------------RQTYTRYQTLELE---KEFHFNRYITRRRRIDIA 288
              :|...|....|.|                |:..|.|.:|:|:   ..|...:|:....|.::|
Human   137 AAQTRGDDTDQQKTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELA 201

  Fly   289 NALSLSERQIKIWFQNRRMKSKKDRTLDSSPEHCG--AGYTAM------LPPLEATSTATTGAPS 345
            .:|.|::.|:||||||:|.|.||.....|:|....  .|..|:      |||:...|.:..|. |
Human   202 ASLGLTQTQVKIWFQNKRSKFKKLLKQGSNPHESDPLQGSAALSPRSPALPPVWDVSASAKGV-S 265

  Fly   346 VPVPMYHHHQTTAAYPAYSHSHSHGYGLLNDYPQQQTHQQYDAYPQ 391
            :|...|        .|.|||.:|.        |.|.|.|:    ||
Human   266 MPPNSY--------MPGYSHWYSS--------PHQDTMQR----PQ 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	23/134 (17%)
		Homeodomain	255..311	CDD:459649	22/74 (30%)
		KLF1_2_4_N	<321..404	CDD:425360	21/79 (27%)
DLX6	NP_005213.3	Homeodomain	168..224	CDD:459649	20/55 (36%)