Protein Alignment ftz and DLX4

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_612138.1
• Gene: DLX4 / 1748
• HGNCID: 2917
• Length: 240
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 60/243 - (24%)
• Similarity: 87/243 - (35%)
• Gaps: 72/243 - (29%)

  Fly   140 VSTKVTASPAPSYDQEY---VTVP-TPSASEDVDYLDVYSPQSQTQKLKNGDFATPPPTTPTSLP 200
            :|....|||..||.:.|   ::.| |..|:....||....|.:.:|
Human    35 LSPTTAASPNLSYSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQ------------------- 80

  Fly   201 PLEGISTPPQS-PGEKSSSAVSQEINHRIVTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRY 264
            ||.|.:..||. ..:.....:|.|.:.|...||                  .|..::.|..|:..
Human    81 PLCGPAEHPQELEADSEKPRLSPEPSERRPQAP------------------AKKLRKPRTIYSSL 127

  Fly   265 QTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKK--------------DRTL 315
            |...|.:.|...:|:....|..:|..|.|::.|:||||||:|.|.||              .||.
Human   128 QLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTF 192

  Fly   316 DSSPEHCGAGYTAMLPPL-------EATSTATTGAPSVPVPMYHHHQT 356
            ..||  |.       |||       :|.:..|:|..:.....|.||.:
Human   193 SVSP--CS-------PPLPSLWDLPKAGTLPTSGYGNSFGAWYQHHSS 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	24/112 (21%)
		Homeodomain	255..311	CDD:459649	19/55 (35%)
		KLF1_2_4_N	<321..404	CDD:425360	10/43 (23%)
DLX4	NP_612138.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..120		12/76 (16%)
		Homeodomain	118..174	CDD:459649	19/55 (35%)