Protein Alignment ftz and DLX1

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_835221.2
• Gene: DLX1 / 1745
• HGNCID: 2914
• Length: 255
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 61/277 - (22%)
• Similarity: 99/277 - (35%)
• Gaps: 107/277 - (38%)

  Fly   194 TTPTSL--------------PPLEGISTPPQSPGE------------------KSSSAVSQEINH 226
            |.|.||              ||.:.:|..|.|.|.                  .|:|:.|:.:.:
Human     5 TMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSASSFSRPLGY 69

  Fly   227 RIVTAPN---------------GAGDFNWSHIEETLASDCKDS-------------KRTRQTYTR 263
            ..|.:.:               |:.....|.:|:..|...|.:             |:.|:..|.
Human    70 PYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGKKIRKPRTI 134

  Fly   264 YQTLELE---KEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSPEHCGAG 325
            |.:|:|:   :.|...:|:....|.::|.:|.|::.|:||||||:|.|.||      ..:..||.
Human   135 YSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKK------LMKQGGAA 193

  Fly   326 YTAMLPPLEATSTA-----TTGAPSVPVPMYHHHQTTAAYPAYSHSHSHGYG-----------LL 374
                   ||.::.|     :.|:|.||             |.::.:.|.|.|           ..
Human   194 -------LEGSALANGRALSAGSPPVP-------------PGWNPNSSSGKGSGGNAGSYIPSYT 238

  Fly   375 NDYPQQQTHQQYDAYPQ 391
            :.||  ..||:....||
Human   239 SWYP--SAHQEAMQQPQ 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	17/100 (17%)
		Homeodomain	255..311	CDD:459649	21/58 (36%)
		KLF1_2_4_N	<321..404	CDD:425360	19/87 (22%)
DLX1	NP_835221.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		9/32 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..118		4/22 (18%)
		Homeodomain	129..185	CDD:459649	20/55 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..230		8/38 (21%)