DRSC/TRiP Functional Genomics Resources

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Protein Alignment ftz and GSX2

DIOPT Version :10

Sequence 1:NP_477498.1 Gene:ftz / 40834 FlyBaseID:FBgn0001077 Length:410 Species:Drosophila melanogaster
Sequence 2:NP_573574.2 Gene:GSX2 / 170825 HGNCID:24959 Length:304 Species:Homo sapiens


Alignment Length:131 Identity:50/131 - (38%)
Similarity:69/131 - (52%) Gaps:16/131 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   209 PQSPGE-------KSSSAVSQEINHRIVTAP-------NGAGD--FNWSHIEETLASDCKDSKRT 257
            ||.||.       .:::|.:..:.|....||       |.|..  |:...:..:.||...:.||.
Human   141 PQQPGSAAAAAAAAAAAAAAAALGHPQHHAPVCTATTYNVADPRRFHCLTMGGSDASQVPNGKRM 205

  Fly   258 RQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSPEHC 322
            |..:|..|.||||:||..|.|::|.|||:||..|:|||:|:||||||||:|.||:........|.
Human   206 RTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGTQRNSHA 270

  Fly   323 G 323
            |
Human   271 G 271

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ftzNP_477498.1 FTZ 1..248 CDD:397787 11/54 (20%)
Homeodomain 255..311 CDD:459649 33/55 (60%)
KLF1_2_4_N <321..404 CDD:425360 2/3 (67%)
GSX2NP_573574.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 116..151 4/9 (44%)
Homeodomain 203..259 CDD:459649 33/55 (60%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 283..304
Blue background indicates that the domain is not in the aligned region.

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