Protein Alignment ftz and Lbx1

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_034821.2
• Gene: Lbx1 / 16814
• MGIID: 104867
• Length: 282
• Species: Mus musculus
• Alignment Length: 267
• Identity: 62/267 - (23%)
• Similarity: 92/267 - (34%)
• Gaps: 70/267 - (26%)

  Fly   129 TTVEQVKKAPAVSTK---VTASPAPSYDQEYVTVPTPSASEDV----DYLDVYSPQSQTQKLKNG 186
            |:.|..|.||....:   :...|.|:...:.:   ||.:.||:    .....||.......|...
Mouse     2 TSKEDGKAAPGEERRRSPLDHLPPPANSNKPL---TPFSIEDILNKPSVRRSYSLCGAAHLLAAA 63

  Fly   187 DFATPPPTTPTSLPPLEG----ISTPPQSPGEKSSSAVSQEINHRIVTAPNGAGDFNWSHIEETL 247
            |...|...      ||.|    ..|.|....|:.:|...:.:...::.|..|..........:|
Mouse    64 DKHAPGGL------PLAGRALLSQTSPLCALEELASKTFKGLEVSVLQAAEGRDGMTIFGQRQT- 121

  Fly   248 ASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKD 312
               .|..:::|..:|.:|..||||.|.:.:|::...|..||..|.|:..|:..||||||.|.|:|
Mouse   122 ---PKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRD 183

  Fly   313 -------------------------RTLDSSPEHCGAG------------YTAMLPPLEATSTAT 340
                                     ..|:.:.|..|.|            .:..|||
Mouse   184 LEEMKADVESAKKLGPSGQMDIVALAELEQNSEASGGGGGGGCGRAKSRPGSPALPP-------- 240

  Fly   341 TGAPSVP 347
             |||..|
Mouse   241 -GAPQAP 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	26/129 (20%)
		Homeodomain	255..311	CDD:459649	22/55 (40%)
		KLF1_2_4_N	<321..404	CDD:425360	9/39 (23%)
Lbx1	NP_034821.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		8/36 (22%)
		Homeodomain	126..182	CDD:459649	22/55 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..282		11/46 (24%)