Protein Alignment ftz and Hoxa10

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_032289.2
• Gene: Hoxa10 / 15395
• MGIID: 96171
• Length: 416
• Species: Mus musculus
• Alignment Length: 306
• Identity: 86/306 - (28%)
• Similarity: 119/306 - (38%)
• Gaps: 108/306 - (35%)

  Fly    66 QEQVTTQTVPPVQPTTPPPKATKRKAEDDAASIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTT 130
            |:|......||.||..|.|:||       :.|....::|..|                    |..
Mouse   142 QQQQQQPPPPPPQPPQPQPQAT-------SCSFAQNIKEESS--------------------YCL 179

  Fly   131 VEQVKKAPAVSTKVTASPAPSYDQEYVTVPTP-----SASEDVDYLDVYSPQSQ----------- 179
            .:...|.|..|.....:|.|       ..|.|     .||..|. :..|...||
Mouse   180 YDAADKCPKGSAAADLAPFP-------RGPPPDGCALGASSGVP-VPGYFRLSQAYGTAKGFGSG 236

  Fly   180 ---TQKLKNGDFATPPPTTPTSLPPL-----------EGI--STPPQ---------SPGEK---S 216
               ||:|.: .|...||......||.           |.:  ||||.         |.|::   :
Mouse   237 GGGTQQLAS-PFPAQPPGRGFDPPPALASGSTEAAGKERVLDSTPPPTLVCTGGGGSQGDEEAHA 300

  Fly   217 SSAVSQEINHRIVTAPN----------------GAGDFNWSHIEETLASDCKDSKRTRQTYTRYQ 265
            ||:.::|::    .||:                |....||        ...|..::.|..||::|
Mouse   301 SSSAAEELS----PAPSENSKASPEKDSLGSSKGENAANW--------LTAKSGRKKRCPYTKHQ 353

  Fly   266 TLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKK 311
            ||||||||.||.|:||.||::|:.::.|::||:||||||||||.||
Mouse   354 TLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKK 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	50/241 (21%)
		Homeodomain	255..311	CDD:459649	33/55 (60%)
		KLF1_2_4_N	<321..404	CDD:425360
Hoxa10	NP_032289.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	40..60
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	81..167		10/31 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	228..345		24/129 (19%)
		Homeodomain	343..399	CDD:459649	33/55 (60%)