Protein Alignment ftz and Hmx3

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_032283.3
• Gene: Hmx3 / 15373
• MGIID: 107160
• Length: 356
• Species: Mus musculus
• Alignment Length: 323
• Identity: 88/323 - (27%)
• Similarity: 128/323 - (39%)
• Gaps: 51/323 - (15%)

  Fly    75 PPVQPTTPPPKATKRKAEDDAASIIAAVEERPSTLRAL----------LTNPVKKLKYTPDYFYT 129
            ||.:| .|||:.....|...||:..||.......|...          |..|  :.:.....|..
Mouse    44 PPPKP-QPPPRTLFAPASAAAAAAAAAAAAAKGALEGAAGFALSQVGDLAFP--RFEIPAQRFAL 105

  Fly   130 TVEQVKKAPAVSTKVTASPAPSYDQEYVTVPTPSASEDVDYLDVYSPQSQTQK------LKNGDF 188
            ....::::||.....|.:||..:      :|.|.|||.....| .||.|.|.:      ||
Mouse   106 PAHYLERSPAWWYPYTLTPAGGH------LPRPEASEKALLRD-SSPASGTDRDSPEPLLK---- 159

  Fly   189 ATPPPTTPTSLPPLEGISTPPQS-PGEKSSSAVSQEINHRI--VTAPNGAGDFNWSHIEETLASD 250
            |.|......|..|.|.|.....| .|:|...||.......:  .||..|:.|:............
Mouse   160 ADPDHKELDSKSPDEIILEESDSEEGKKEGEAVPGAAGTTVGATTATPGSEDWKAGAESPEKKPA 224

  Fly   251 CKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTL 315
            |: .|:||..::|.|..:||..|...||::...|..:|.:|.|:|.|:||||||||.|.|:....
Mouse   225 CR-KKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAA 288

  Fly   316 D---SSPEHCGAGYTAMLPPLEATSTATTGAPS-----VPV---------PMYHHHQTTAAYP 361
            :   ::..|..|.....:|.|...::|..||.:     |||         |:|:.|...::.|
Mouse   289 ELEAANLSHAAAQRIVRVPILYHENSAAEGAAAAAGAPVPVSQPLLTFPHPVYYSHPVVSSVP 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	47/191 (25%)
		Homeodomain	255..311	CDD:459649	25/55 (45%)
		KLF1_2_4_N	<321..404	CDD:425360	14/55 (25%)
Hmx3	NP_032283.3	Homeodomain	228..284	CDD:459649	25/55 (45%)