Protein Alignment ftz and DBX1

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001025036.2
• Gene: DBX1 / 120237
• HGNCID: 33185
• Length: 343
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 82/321 - (25%)
• Similarity: 121/321 - (37%)
• Gaps: 71/321 - (22%)

  Fly   111 ALLTNPVKKLKYTPDYFYTTVEQV------KKAPAVSTKVTASPAPSYDQEYVTVPTPSASEDVD 169
            :.|...:.::...|.|...:|...      :.||...|...||...|        |.|.:.....
Human    38 SFLVEDLIRISRPPAYLPRSVPTASMSPPRQGAPTALTDTGASDLGS--------PGPGSRRGGS 94

  Fly   170 YLDVYSPQSQTQKLKNGDFA--TPPPTTPTSLPPLEGISTPPQS-----------PGEKSSSAVS 221
            ....:||.|:|..||.|..|  :..|.|.||...|:  |.||::           |..:||...:
Human    95 PPTAFSPASETTFLKFGVNAILSSGPRTETSPALLQ--SVPPKTFAFPYFEGSFQPFIRSSYFPA 157

  Fly   222 QEINHRIVTAPNGAGDFNWSHIEETLASDCKDSK--RTRQTYTRYQTLELEKEFHFNRYITRRRR 284
               :..:|..|   |.|:|     .||:..|..:  ..|..::..|...|||.|...:||::..|
Human   158 ---SSSVVPIP---GTFSW-----PLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDR 211

  Fly   285 IDIANALSLSERQIKIWFQNRRMK--SKKDRTLDSS---------------PEHCGAGYTAMLPP 332
            ..:|..|.|.:.|:||||||||||  :.|:|.|.||               |:....|...   |
Human   212 KKLAAKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKG---P 273

  Fly   333 LEATSTATTGAPSVPVPMYH-----HHQTTAAYPA---YSHSHSHGYGLLNDYPQQQTHQQ 385
            .........|:||..: .||     .|......|.   .|.:||...|..:|:...:..::
Human   274 GNEEEEEGPGSPSHRL-AYHASSDPQHLRDPRLPGPLPPSPAHSSSPGKPSDFSDSEEEEE 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	36/155 (23%)
		Homeodomain	255..311	CDD:459649	23/59 (39%)
		KLF1_2_4_N	<321..404	CDD:425360	14/73 (19%)
DBX1	NP_001025036.2	PRK12323	<49..182	CDD:481241	38/153 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	56..100		9/51 (18%)
		Homeodomain	184..238	CDD:459649	23/53 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..343		20/98 (20%)