Protein Alignment ftz and Hoxb2

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_598793.2
• Gene: Hoxb2 / 103889
• MGIID: 96183
• Length: 354
• Species: Mus musculus
• Alignment Length: 332
• Identity: 86/332 - (25%)
• Similarity: 125/332 - (37%)
• Gaps: 82/332 - (24%)

  Fly    99 IAAVEERPSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAPAVSTKVTASPAPSYDQEYVTVPTPS 163
            |..:..:||....|.:.|             .|.:..:..::.......|.|..:|.:.::...:
Mouse     9 IGFINSQPSLAECLTSFP-------------AVLETFQTSSIKESTLIPPPPPLEQTFPSLQLGA 60

  Fly   164 ASEDVDYLDVYSPQSQTQKLKNGDFATPPPTTPTSLPPLE--------GISTPPQ---SPGEKSS 217
            ::       :..|.||.| ..:|.....||..|.:.|..|        ....|.|   ||...:|
Mouse    61 ST-------LQRPGSQKQ-AGDGPALRSPPPLPVAPPAPEFPWMKEKKSTKKPSQSAASPSPAAS 117

  Fly   218 SAVSQEINHRIVTAPNGAGDFNWSHIEETLASDC--KDSKRTRQTYTRYQTLELEKEFHFNRYIT 280
            |..:.|:.    :..:|.|           ..:|  ..|:|.|..||..|.||||||||||:|:.
Mouse   118 SVRASEVG----SPSDGPG-----------LPECGGSGSRRLRTAYTNTQLLELEKEFHFNKYLC 167

  Fly   281 RRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSPE--------HCGAGYTAMLPPLEATS 337
            |.||::||..|.|:|||:|:||||||||.|:.......||        ...||..|..|.:....
Mouse   168 RPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPEGEPGGPSAQDDAGEPAEEPTVSPGD 232

  Fly   338 TAT-----------------TGAPSVPVPMYHHHQTTAAYPAYSHSHSHGYGLLNDYPQQQTHQQ 385
            .||                 .|||...:|........|:.|        |..:|....:|.....
Mouse   233 VATHRLREACFHPAEAAQGPRGAPPSALPATTLESVGASSP--------GCTMLRAGGRQSEPLP 289

  Fly   386 YDAYPQQ 392
            .||.|::
Mouse   290 EDACPER 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	28/159 (18%)
		Homeodomain	255..311	CDD:459649	35/55 (64%)
		KLF1_2_4_N	<321..404	CDD:425360	18/89 (20%)
Hoxb2	NP_598793.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..143		24/126 (19%)
		Antp-type hexapeptide	92..97		1/4 (25%)
		Homeodomain	142..198	CDD:459649	35/55 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	193..231		10/37 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	246..295		11/56 (20%)