DRSC/TRiP Functional Genomics Resources

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Protein Alignment ftz and nkx3-2

DIOPT Version :10

Sequence 1:NP_477498.1 Gene:ftz / 40834 FlyBaseID:FBgn0001077 Length:410 Species:Drosophila melanogaster
Sequence 2:XP_002940787.1 Gene:nkx3-2 / 100497965 XenbaseID:XB-GENE-876834 Length:329 Species:Xenopus tropicalis


Alignment Length:263 Identity:59/263 - (22%)
Similarity:97/263 - (36%) Gaps:79/263 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 PPPKATKRKAEDDAASIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAPAVSTKVTA 146
            |.|.||:.:..|..|::.::....|.:::|:|..              ..|:.:..|.:.:.|  
 Frog    43 PEPGATRCRTLDPMAAVRSSGSLTPFSIQAILNR--------------KEERARTFPRLGSAV-- 91

  Fly   147 SPAPSY----DQEY--------VTVPTPSASEDVDYLDVYSPQSQTQKLKNGDFATPPPTTPTSL 199
            |||..:    :.|.        .|..|.:..|...:      .|.:...:.|:...|..|.....
 Frog    92 SPACCWRIFGETEADGLGSLCGGTPGTGAGGEPAGW------DSDSALSEEGELGRPGDTGERKK 150

  Fly   200 P-PLE-------------------GISTPPQSPGEKSSSAVSQEINHRIVTAPNGAGDFNWSHIE 244
            . |||                   |...|..||.::....                        |
 Frog   151 QRPLEARTKGEDEEETPGCSDCEIGAGVPDPSPPDEDPKC------------------------E 191

  Fly   245 ETLASDCKD-SKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMK 308
            :.:....|. .||:|..::..|..|||:.|:..||::...|.|:|.:|.|:|.|:||||||||.|
 Frog   192 QLMLEPPKQRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYK 256

  Fly   309 SKK 311
            :|:
 Frog   257 TKR 259

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ftzNP_477498.1 FTZ 1..248 CDD:397787 31/197 (16%)
Homeodomain 255..311 CDD:459649 26/55 (47%)
KLF1_2_4_N <321..404 CDD:425360
nkx3-2XP_002940787.1 Homeodomain 203..259 CDD:459649 26/55 (47%)
Blue background indicates that the domain is not in the aligned region.

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