Protein Alignment ftz and nkx6-3

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: XP_002932753.1
• Gene: nkx6-3 / 100489301
• XenbaseID: XB-GENE-478609
• Length: 255
• Species: Xenopus tropicalis
• Alignment Length: 246
• Identity: 60/246 - (24%)
• Similarity: 94/246 - (38%)
• Gaps: 81/246 - (32%)

  Fly   138 PAVSTKVTAS----PA--------PSYDQEYVTVPTPSASEDVDYLDVYSPQSQTQKLKNGDFAT 190
            |..||::.:|    ||        ||....::...||....|:                   .:.
 Frog    12 PPYSTEMKSSGCQFPAHTPFHKLNPSVLGCHLPSGTPHGISDI-------------------LSR 57

  Fly   191 PPPTTPTSL----PPLEGI---STPPQSPGEKSSSAVSQEINHRIVTAPNGAGDFN-----WSHI 243
            |.|.:.:.:    |.::|.   |.|....||:.|           :...:|....|     |:.|
 Frog    58 PLPASHSGMFPGYPTVQGYGSSSVPGSCYGEQGS-----------ILTKSGTPYTNQSRGCWTDI 111

  Fly   244 EE---------TLASDCKDS---KRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSER 296
            |:         :..|:.:.|   |.||.|:|.:|...|||.|...:|:....|..:|.:|.:||.
 Frog   112 EQDWRGGNRALSSVSNTEGSSRKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAFSLGMSES 176

  Fly   297 QIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPLEATSTATTG--APS 345
            |:|:||||||.|.:|...:::             |.|.:.||...|  .||
 Frog   177 QVKVWFQNRRTKWRKKSAVET-------------PGLPSLSTRGPGDLTPS 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	25/142 (18%)
		Homeodomain	255..311	CDD:459649	25/55 (45%)
		KLF1_2_4_N	<321..404	CDD:425360	7/27 (26%)
nkx6-3	XP_002932753.1	Homeodomain	133..191	CDD:459649	25/57 (44%)