Protein Alignment Scr and Nkx6-3

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_083278.1
• Gene: Nkx6-3 / 74561
• MGIID: 1921811
• Length: 262
• Species: Mus musculus
• Alignment Length: 195
• Identity: 55/195 - (28%)
• Similarity: 87/195 - (44%)
• Gaps: 36/195 - (18%)

  Fly   210 LSTRDISPKL---SPSSVVESVARSL---NKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNV 268
            ||...:.|:|   :|..:.:.::|.:   |..:|.| ....|...||    |..||..||   .|
Mouse    38 LSPPGLGPQLAAGTPHGITDILSRPVATPNSSLLSG-YPHVAGFGGL----SSQGVYYGP---QV 94

  Fly   269 PMHSPGGGDSDSE-----SDSGNE-AGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQ 327
            ...|..|.:..:.     :|:|.: .||::..    .|.|.  |....:|          :.|..
Mouse    95 GSFSKAGNEYPTRTRNCWADTGQDWRGSARPC----SNTPD--PLSDTIH----------KKKHT 143

  Fly   328 RTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNIVP 392
            |.::|.:|...|||.|...:||....|..:|::|.:||.|:|:||||||.||:|:..:...:..|
Mouse   144 RPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKSALEPSSSTP 208

  Fly   393  392
            Mouse   209  208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	25/55 (45%)
Nkx6-3	NP_083278.1	Homeodomain	139..197	CDD:459649	25/57 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..237		2/12 (17%)