Protein Alignment Scr and Vax2

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_072159.2
• Gene: Vax2 / 64572
• RGDID: 621133
• Length: 292
• Species: Rattus norvegicus
• Alignment Length: 273
• Identity: 70/273 - (25%)
• Similarity: 98/273 - (35%)
• Gaps: 93/273 - (34%)

  Fly   273 PGG---------GDSDSESDSGNE-----AGSSQNSGNGKKNPPQIYPWMKRVHLGTST-VNANG 322
            |||         |..|..:|:|:.     ||:|.:|..|.:...           |.|. ..|.|
  Rat    18 PGGRSGCRGEHRGAEDLRADTGSTSPREIAGTSASSPAGSRESG-----------GDSDGQQALG 71

  Fly   323 ET-----------------------------KRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIA 358
            ||                             ||.|||:|..|...||.||...:|:..|.|.|:|
  Rat    72 ETDHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELA 136

  Fly   359 HALCLTERQIKIWFQNRRMKWKKEHKMASMNIVPYHMGPYGHPYHQFDIHPSQFAHLSAXDAWHF 423
            ..|.|:|.|:|:||||||.|.||:...                    |:  .:.|..||.:|:..
  Rat   137 RQLNLSETQVKVWFQNRRTKQKKDQSR--------------------DL--EKRASSSASEAFAT 179

  Fly   424 SGTGXRLNQ--LYQEPYQTAAAASAASGYQSQDGGPIGGGSVGVGGGAGGPGSLANGGSNGSGPN 486
            |.....|.|  |...|...:..|             :..|..|:..|..|. ||.:..::....|
  Rat   180 SNVLRLLEQGRLLSVPRAPSLLA-------------LSPGLPGLTAGHRGT-SLGDPRNSSQRLN 230

  Fly   487 SLFASAASSSQAP 499
            .:.:::|||...|
  Rat   231 PMPSASASSPLPP 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	28/55 (51%)
Vax2	NP_072159.2	vax upstream domain	74..101		0/26 (0%)
		homeobox	102..161		30/58 (52%)
		Homeodomain	103..159	CDD:459649	28/55 (51%)
		vax downstream domain	182..193		3/10 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..241		8/29 (28%)
		vax terminal domain	266..274