DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scr and hoxb6b

DIOPT Version :9

Sequence 1:	NP_001368995.1	Gene:	Scr / 40833	FlyBaseID:	FBgn0003339	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_571613.1	Gene:	hoxb6b / 58053	ZFINID:	ZDB-GENE-000823-7	Length:	224	Species:	Danio rerio

Alignment Length:	237	Identity:	89/237 - (37%)
Similarity:	114/237 - (48%)	Gaps:	47/237 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 ISCKYAND--PVT-PGGSG---------GGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISP 217
            :|..:.|.  ||: |||..         ..|.:.|..:..||.....|.|.
Zfish     1 MSSYFVNSTFPVSLPGGQESFLGQIPLYSSGYTDSLRHYPSATFGATNVQD-------------- 51

  Fly   218 KLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDS---- 278
            |:..||..:...     ||.|.|.:.:|......|.:..:..|...|::.         ||
Zfish    52 KVYTSSYYQQAG-----GVFGRSGSTSACDYSTPNIYRSADRSCAIGSLE---------DSLVLT 102

  Fly   279 -DSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKE 342
             |.......|.|:.:......|....:||||:|::.......:.|  :|.|.:|||:||||||||
Zfish   103 QDQCKTDCTEQGTERYFSTEDKPCTPVYPWMQRMNSCNGMPGSTG--RRGRQTYTRFQTLELEKE 165

  Fly   343 FHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 384
            |||||||||||||||:||||||||||||||||||||||||:|
Zfish   166 FHFNRYLTRRRRIEISHALCLTERQIKIWFQNRRMKWKKENK 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	48/52 (92%)
hoxb6b	NP_571613.1	Antp-type hexapeptide	129..134		3/4 (75%)
hoxb6b	NP_571613.1	Homeobox	151..203	CDD:278475	47/51 (92%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.810