DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scr and hoxa1a

DIOPT Version :9

Sequence 1:	NP_001368995.1	Gene:	Scr / 40833	FlyBaseID:	FBgn0003339	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_571611.1	Gene:	hoxa1a / 58051	ZFINID:	ZDB-GENE-000823-5	Length:	329	Species:	Danio rerio

Alignment Length:	356	Identity:	94/356 - (26%)
Similarity:	128/356 - (35%)	Gaps:	94/356 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 SGGGAGGSGGVVPSGGTNGGQGSAGAATPGANDYFPAAAAYTPNLYPNTPQAHYANQAAYGGQGN 106
            ||||.|||||   |.......|..|.:|      |.::.|...|              :..|.
Zfish    11 SGGGDGGSGG---SCSVRAFHGDHGLST------FQSSCAVRLN--------------SCSGD-- 50

  Fly   107 PDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQQQHPQQQQQQQQANISCKYAN 171
                       :|.:.....|.           |...|.||....|.|        ..:|..|:.
Zfish    51 -----------ERFMSNISSQD-----------VINSQPQQAGSYQSP--------GTLSITYSA 85

  Fly   172 DPVTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVAR------ 230
            .|       ..|........|....|.:...|::.||      ..|.:...::..:|.:
Zfish    86 HP-------SYGTQSFCTGYNHYALNQDVESSVSFPQ------CGPLVYSGNISSTVVQHRHHRH 137

  Fly   231 --SLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQN 293
              |.....|.|.....:|..|.:::.:......|..|...|:|.|......|....|...|.:.:
Zfish   138 GYSSGNVHLHGQFQYGSATYGNSSDQANLTFVAGCSNPLSPLHVPHHDACCSPLSDGVPTGQTFD 202

  Fly   294 SGNGKKNPPQIYPWMKRVHLGTSTVNA-----NGETKRQRTSYTRYQTLELEKEFHFNRYLTRRR 353
            ....|:|||:             |..|     .|:....||:::..|..|||||||||:||||.|
Zfish   203 WMKVKRNPPK-------------TGKAGEYGFGGQPNTVRTNFSTKQLTELEKEFHFNKYLTRAR 254

  Fly   354 RIEIAHALCLTERQIKIWFQNRRMKWKKEHK 384
            |:|||.:|.|.|.|:||||||||||.||..|
Zfish   255 RVEIAASLQLNETQVKIWFQNRRMKQKKREK 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	35/52 (67%)
hoxa1a	NP_571611.1	Antp-type hexapeptide	200..205		0/4 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	208..227		6/31 (19%)
		Homeobox	229..281	CDD:278475	35/51 (69%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	277..329		6/9 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910