Protein Alignment Scr and Dfd

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_001688962.1
• Gene: Dfd / 5667644
• VectorBaseID: AGAMI1_000814
• Length: 577
• Species: Anopheles gambiae
• Alignment Length: 541
• Identity: 149/541 - (27%)
• Similarity: 213/541 - (39%)
• Gaps: 128/541 - (23%)

  Fly    33 GAGNSSAG---GSGGGAGGSGGVVPSGGTNGGQGSAGAATPGANDYFPAAAAYTPNLYPNTPQAH 94
            |||:::.|   |.|||.||.||    ||..||.|...||   .|||..:...:    |.:.|..|
Mosquito    85 GAGSNAEGEERGGGGGVGGGGG----GGAEGGGGGVSAA---YNDYSSSMVGH----YYHHPHHH 138

  Fly    95 ---------YANQAAYGGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQ 150
                     :|:..::.|..:|                 .|.|.......|.|..........|.
Mosquito   139 HHHHHHHHPHAHHPSHNGYMSP-----------------VQMQSTSSGLIAPAITTLPPSVSTAA 186

  Fly   151 QQHPQQQQQQQQANISCKYANDPVTPGGSGGGGVSGSNNNNNS--------ANSNNNNSQSLASP 207
            .......|.....||:..|.|          |..|.|...:.|        ..:...|:.
Mosquito   187 SNSSVSNQNSFPTNITSGYYN----------GYYSASTEGHTSIMDTPLQCVGTEVTNTA----- 236

  Fly   208 QDLSTRDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAAAG---------LNNNHSGSGVSGGP 263
              |..:::..||. ..:.|:.........||..|....|::.         |..:.|...:....
Mosquito   237 --LGLQELGMKLD-RRIEEAAPTGQQLQELGMRLRCDDASSDQDEFLDEERLMLDQSPDELDSND 298

  Fly   264 GNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANG------ 322
            |:::         |.:|::|.|.:...:.:.|.     ..||||||::|:...   |||
Mosquito   299 GDID---------DLESDNDLGEDVMHATSDGE-----RIIYPWMKKIHVAGV---ANGSFQPGM 346

  Fly   323 ETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMAS 387
            |.|||||:|||:|.||||||||:||||||||||||||.|.|:|||||||||||||||||::|:.:
Mosquito   347 EPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPN 411

  Fly   388 MNIVPYHMGPYGHPYHQFDIHPSQFAHLSAXDAWHFSGTGXRLNQLYQEPYQTAAAASAASGYQS 452
            ...|....|..                 |. :|...:|.. .:|...:....::...|..|..|.
Mosquito   412 TKNVRKKNGDQ-----------------SKSNASGSTGQSGVINNQKKSRKVSSTTLSTKSKQQQ 459

  Fly   453 Q--DGGPIGGGSVGVGGGAGGPGSLANGGS----NGSGPNSLFASAASSSQAPDCIKYPQEFXSQ 511
            |  ....:...|:.......|..:..|..|    :.|..|:....|..::.:.:.|:  .|. ||
Mosquito   460 QTLQNECLRTDSLESMADVHGTITTINTSSSQYMSSSDVNNTLPMANGTNNSSNTIR--NEHLSQ 522

  Fly   512 VIIRQQ--HQQQQDNSMDRNQ 530
               .||  |.|||.:.:.::|
Mosquito   523 ---HQQLPHNQQQHHQLRQSQ 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	48/55 (87%)
Dfd	XP_001688962.1	Homeodomain	349..405	CDD:459649	48/55 (87%)