Protein Alignment Scr and nkx6.3

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001159612.1
• Gene: nkx6.3 / 558978
• ZFINID: ZDB-GENE-070810-7
• Length: 272
• Species: Danio rerio
• Alignment Length: 223
• Identity: 62/223 - (27%)
• Similarity: 100/223 - (44%)
• Gaps: 42/223 - (18%)

  Fly   184 VSGSNNNNNSANSNNNNSQS----LASPQD---LSTRDISPKL---SPSSVVESVARSLNKG--- 235
            :|||...|||.|...::.::    .:.|..   |...:|:.:|   :|..:.:.::||:..|
Zfish     5 ISGSFLFNNSLNQFPSDIKAPVCQYSIPNSFYKLGPANINSQLQAGTPHGISDILSRSMVSGPGT 69

  Fly   236 ---VLG----GSLAAAAAAAGL--NNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNE-AGS 290
               :.|    |.......:.|:  |.:::.||:|..|..| |......|..|....|.|.| .|:
Zfish    70 PALLSGYPSMGGFGTTVPSPGVYYNRDYTPSGLSTFPKPV-VECAGMKGKSSSCWVDGGYEWRGA 133

  Fly   291 SQNSGNGK-KNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRR 354
            .|..||.. .||..:                 |:.|..|.:::.:|...|||.|...:||....|
Zfish   134 RQQCGNNMGHNPENV-----------------GKKKHTRPTFSGHQIFALEKTFEQTKYLAGPER 181

  Fly   355 IEIAHALCLTERQIKIWFQNRRMKWKKE 382
            ..:|::|.:||.|:|:||||||.||:|:
Zfish   182 ARLAYSLGMTESQVKVWFQNRRTKWRKK 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	24/55 (44%)
nkx6.3	NP_001159612.1	Homeodomain	150..208	CDD:459649	24/57 (42%)