Protein Alignment Scr and crx

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001016021.1
• Gene: crx / 548775
• XenbaseID: XB-GENE-478452
• Length: 290
• Species: Xenopus tropicalis
• Alignment Length: 255
• Identity: 55/255 - (21%)
• Similarity: 87/255 - (34%)
• Gaps: 62/255 - (24%)

  Fly   308 MKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWF 372
            |..:|..........:.:|:||::||.|...||..|...||.....|.|:|..:.|.|.::::||
 Frog    22 MDLLHSAVGYPTTPRKQRRERTTFTRAQLDILEALFAKTRYPDIFMREEVALKINLPESRVQVWF 86

  Fly   373 QNRRMKWKKEHKMASMNIVPYHM-----------------GPYGHPYHQFDIHPSQFAHLSAXDA 420
            :|||.|.:::.:.::....|...                 |.|..|.....:.||..|
 Frog    87 KNRRAKCRQQQQQSTGQAKPRPAKKKTSPARETNSEASTNGQYSPPPPGTAVTPSSTA------- 144

  Fly   421 WHFSGTGXRLNQLYQEPYQTAAAASAASGYQSQDGGPI------------GGGS---VGVGGGA- 469
               |.|. ..:.....|.....:|:.....|...|.|:            ||.|   .|:..|:
 Frog   145 ---SATVSIWSPASISPIPDPLSAATTPCMQRSAGYPMTYSQAPAYTQSYGGSSSYFTGLDCGSY 206

  Fly   470 --------GGPGSLAN-------GGSNGSGPNSLFASAASSSQ----APDCIKYPQEFXS 510
                    ..||:..:       |......|.||.|....:|.    :.||:.|..:. |
 Frog   207 LSPMHPQLSAPGATLSPIATPTMGSHLSQSPASLSAQGYGASSLGFTSVDCLDYKDQTAS 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	22/55 (40%)
crx	NP_001016021.1	Homeodomain	39..94	CDD:459649	22/54 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..144		6/50 (12%)
		TF_Otx	152..236	CDD:427350	13/83 (16%)