Protein Alignment Scr and Dbx2

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001418946.1
• Gene: Dbx2 / 541457
• RGDID: 1359605
• Length: 377
• Species: Rattus norvegicus
• Alignment Length: 290
• Identity: 65/290 - (22%)
• Similarity: 107/290 - (36%)
• Gaps: 81/290 - (27%)

  Fly   178 GSGGGGVSGSNNNNNSANSNNNNSQSLASPQDL------------STRDISPKLSPSSVVESVAR 230
            ||....:......:.||:.:....::|...:|.            |.|..||:| |.....::..
  Rat     3 GSDTPSIPVVKTQSGSADCSRTLPEALLRAKDALRSPDPAGALSRSPRTRSPRL-PGQRARTMLP 66

  Fly   231 SLNKGVLGG--SLAAAAAAAGL---------------NNNHSGSGVSGGPGNVN----------- 267
            |......|.  .:.|::|..||               |...:|:|.:..|.:..
  Rat    67 SAVAAQAGAYWDVVASSALLGLPAPGFGSLGKSFLIENLLRAGAGPTHAPPSPRPAAGPECPQLR 131

  Fly   268 ------VPMH-SPGG------------GDSDSESDSGNEAGS---------------SQNSGNGK 298
                  ||:. .|.|            |.:..|.||..:..:               |...|...
  Rat   132 SLPANPVPLKLCPAGPFGARWAFQMPPGRAPGERDSAFQPSAPVPSKPFLLSAGPFYSACCGGSC 196

  Fly   299 KNPPQIYPWMKRVH-LGTSTVNANGETKR---QRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAH 359
            :.|.....:.:..| |...|.::|.:.:|   :|..::..|...|||.|...:|:::..|.::|.
  Rat   197 RRPASPTAFSREEHGLPLLTQDSNSKARRGILRRAVFSEDQRKALEKMFQKQKYISKTDRRKLAI 261

  Fly   360 ALCLTERQIKIWFQNRRMKWK--KEHKMAS 387
            :|.|.|.|:|||||||||||:  ||.::.|
  Rat   262 SLGLKESQVKIWFQNRRMKWRNSKEKEVLS 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	25/60 (42%)
Dbx2	NP_001418946.1	PHA03247	<39..186	CDD:223021	24/147 (16%)
		Homeodomain	229..283	CDD:459649	24/53 (45%)