Protein Alignment Scr and en1b

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001013516.1
• Gene: en1b / 541371
• ZFINID: ZDB-GENE-980526-6
• Length: 274
• Species: Danio rerio
• Alignment Length: 261
• Identity: 72/261 - (27%)
• Similarity: 92/261 - (35%)
• Gaps: 94/261 - (36%)

  Fly   190 NNNSANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLN---KGVLGGSLAAAAAAAGLN 251
            :.||.:|..:.|.|      ||....||.:.|....:...|:.|   ..:|......
Zfish     6 DQNSRDSTESESVS------LSPNIPSPPILPHQAAQQAHRTTNFFIDNILRPDFGC-------- 56

  Fly   252 NNHSGS---GVSGGPGNVNV----PMHS-----PGGGDSDSESDSGNEAGSSQNS------GNGK 298
            ....||   ..:.|..|||.    |.|:     .....|||.|.|.:.:.||:.|      |||.
Zfish    57 KKDPGSRDRAQTSGRENVNPMVIRPSHNSSLCQDSNCSSDSTSSSSSSSPSSKQSSVKHFEGNGS 121

  Fly   299 ------KNPPQIYPWMKRVHLGTSTVNANG----------------------------------- 322
                  :|.|.|           ..|||||
Zfish   122 TAARNGENTPSI-----------MMVNANGGTPPAKESQPLLWPAWVYCTRYSDRPSSGPRTRKL 175

  Fly   323 -------ETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWK 380
                   |.||.||::|..|...|:.||..|||:|.:||..:|..|.|.|.||||||||:|.|.|
Zfish   176 KKKKSEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQSLAQELNLNESQIKIWFQNKRAKIK 240

  Fly   381 K 381
            |
Zfish   241 K 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	29/55 (53%)
en1b	NP_001013516.1	Homeodomain	186..241	CDD:459649	28/54 (52%)
		Engrail_1_C_sig	242..272	CDD:431338	72/261 (28%)